ApoE phenotype influences plasma ASP in hyperapoB subjects

Cianflone, Katherine; Phélis, Steve; Davignon, Jean; Gilfix, Brian M.

doi:10.1016/s0021-9150(03)00289-2

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“…23 Moreover, apo E- is a protein that regulates many functions beyond affecting lipoprotein metabolism. 8 For instance, apo E- gene polymorphism has been found to influence serum levels of C-reactive protein, 24 levels of acylation-stimulating protein, 25 or dietary cholesterol absorption. 20 In this context, the apo E- polymorphism could affect the rate of purine intestinal absorption, the rate of intestinal uric acid elimination, or even the rate of hepatic and/or vascular uric acid production.…”

Section: Discussionmentioning

confidence: 99%