Apoptosis Corrected Proliferation Fraction in Childhood All is Related to Karyotype

Ball, Lynne M.; Pyesmany, Allen F.; Yhap, Margaret; Lannon, Christopher L.; Henry, M.; Laybolt, K.; Riddell, D. Christie; Velzen, D. van

doi:10.1007/978-1-4615-4811-9_32

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2006

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“…Ball et al reported similar results from studies using very involved methodology (8). This feature may serve as an additional risk factor for treatment stratification.…”

Section: Discussionmentioning

confidence: 69%

“…Cells accumulate due to the shift from differentiation to proliferation. In ALL for instance the turnover time of a dividing malignant cell may show low levels in certain subtypes (8). This may be one of the reasons why particularly in this disease the mitotic yield of uncultivated or short-term culture preparations may be notoriously low as opposed to other types of bone marrow malignancy.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Proliferation studies on chromosome preparations of bone marrow in hematological disease

Ju¹,

Pohl²,

Rausch³

et al. 2006

Oncol Rep

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“…Ball et al reported similar results from studies using very involved methodology (8). This feature may serve as an additional risk factor for treatment stratification.…”

Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%