Appearing and disappearing CT scan abnormalities and seizures.

Sethi, Prahlad K.; Kumar, Br; Madan, V S; Mohan, VS Krishna

doi:10.1136/jnnp.48.9.866

Cited by 80 publications

(38 citation statements)

References 7 publications

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“…While these lesions were initially suspected to be tuberculomas [34], their spontaneous resolution on serial imaging studies created confusion to the point that it was considered that they just represented rupture of the blood-brain barrier and thus, were seen as the consequence and not the cause of the seizure disorder [35]. By that time, reports from Mexico also brought to the attention of the medical community the same disturbing images, commenting on their possible cysticercotic nature and suggesting that they represented acute phases of infestation of the nervous system by these parasites [36,37].…”

Section: Disappearing Ct Enhancing Lesions In Indian Patients: An Evomentioning

confidence: 97%

Taenia solium Cysticercosis — The lessons of history

Brutto

Garcı́a

2015

Journal of the Neurological Sciences

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Section: Disappearing Ct Enhancing Lesions In Indian Patients: An Evomentioning

confidence: 97%

Taenia solium Cysticercosis — The lessons of history

Brutto

Garcı́a

2015

Journal of the Neurological Sciences

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“…In several retrospective studies the authors have suggested that spontaneous resolution may vary from as early as 6 weeks to as late as 75 weeks. 15,42,43,50 Even greater persistence has been observed. Various authors have noted a wide variation in the rates of complete resolution.…”

Section: Radiological Featuresmentioning

confidence: 97%

Single enhancing computerized tomography–detected lesion in immunocompetent patients

Garg¹

2002

FOC

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Single enhancing computerized tomography (CT)–documented lesions may occur in several infectious and neoplastic diseases of the central nervous system and are the most common radiological abnormality seen in patients with acute-onset seizures in India and many other developing countries. Similar CT-documented lesions have also been reported in the developed world where these lesions are often considered to be caused by neoplasms or tuberculoma. Histopathological studies in India and even in some developed countries revealed that neurocysticercosis (NCC) is the most likely cause of these lesions provided they fulfill a rigid set of clinical and radiological criteria. Single cysticer-cus granuloma measures less than 20 mm in diameter, may be associated with cerebral edema not severe enough to produce midline shift, and occur in patients with seizures, normal neurological status, and no evidence of active systemic disease. When these lesions resolve spontaneously, either disappearing or changing into a calcified nodule, the diagnosis of NCC is very likely. The second most common cause of these CT-detected lesions is tuberculoma; in patients with these lesions similar clinical and neuroimaging features are also present. Few authors believe that in poor and developing countries, where both tuberculosis and NCC are common, it is difficult to differentiate between tuber-culoma and a single cysticercal granuloma. The most interesting feature of these solitary enhancing lesions is their spontaneous disappearance within weeks or months. Some lesions “heal” by becoming calcified. These patients require only antiepileptic therapy, and this medication may be withdrawn safely after the lesion has resolved on CT scanning. In several studies provision of anticysticercal drugs has been attempted, but because of conflicting results, their role in the management of these single lesions is uncertain. Neurosurgeons have a very limited role to play. In very rare situations, if the lesion increases in size and if focal neurological deficits manifest or seizures are uncontrolled, a brain biopsy sample may be required and histopathological evaluation performed to establish the correct diagnosis.

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“…3,5 In several other studies, [6][7][8] these CT lesions have been treated with anticysticercal drugs, however, with conflicting results. Neurocysticercosis and Tuberculoma are the commonest ring forming granulomas and they respond well with their respective treatment.…”

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confidence: 99%

Non-Epileptic Manifestations in Patients With Single Enhancing Computed Tomography Lesions in a Tertiary Care Centre of Bihar

Kumar¹,

Dinkar²,

Kumar³

2017

jemds

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BACKGROUNDSingle small ring enhancing computed tomography lesion is a clinicoradiological abnormality being reported more frequently as imaging of the brain becomes more prevalent. It is a common abnormality on imaging in young patients of low socioeconomic status presented with acute symptomatic seizures in tropical and developing countries like India. Neurocysticercosis and Tuberculoma are the commonest ring forming granulomas. Apart from the seizure, many varieties of other neurological manifestations have been observed in these cases of single ring enhancing lesions found on the computed tomography scan of brain.The objective of the present study is to identify the non-epileptic manifestations of single ring enhancing computed tomography lesions.

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Appearing and disappearing CT scan abnormalities and seizures.

Cited by 80 publications

References 7 publications

Taenia solium Cysticercosis — The lessons of history

Taenia solium Cysticercosis — The lessons of history

Single enhancing computerized tomography–detected lesion in immunocompetent patients

Non-Epileptic Manifestations in Patients With Single Enhancing Computed Tomography Lesions in a Tertiary Care Centre of Bihar

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