Application and optimization of the rate response function in dual-chamber pacemakers: Prospective, randomized, cross-over clinical trial study protocol

Świerżyńska, Ewa; Główczyńska, Renata; Sterliński, Maciej; Krauze, Natasza; Cacko, Andrzej; Kołodzińska, Agnieszka; Opolski, Grzegorz; Szumowski, Łukasz; Grabowski, Marcin

doi:10.33963/kp.a2022.0230

Cited by 1 publication

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is especially true in patients with a high percentage of atrial pacing. However, with regard to the impact of the rate-response function on the change in patients’ physical capacity, the data are not clear; there are only a few results from contemporary studies available, though further studies exploring this issue are in progress [ 135 ].…”

Section: Discussionmentioning

confidence: 99%

Rate-Responsive Cardiac Pacing: Technological Solutions and Their Applications

Świerżyńska

Oręziak

Główczyńska

et al. 2023

Sensors

Self Cite

View full text Add to dashboard Cite

Modern cardiac pacemakers are equipped with a function that allows the heart rate to adapt to the current needs of the patient in situations of increased demand related to exercise and stress ("rate-response" function). This function may be based on a variety of mechanisms, such as a built-in accelerometer responding to increased chest movement or algorithms sensing metabolic demand for oxygen, analysis of intrathoracic impedance, and analysis of the heart rhythm (Q-T interval). The latest technologies in the field of rate-response functionality relate to the use of an accelerometer in leadless endocavitary pacemakers; in these devices, the accelerometer enables mapping of the mechanical wave of the heart's work cycle, enabling the pacemaker to correctly sense native impulses and stimulate the ventricles in synchrony with the cycles of atria and heart valves. Another modern system for synchronizing pacing rate with the patient's real-time needs requires a closed-loop system that continuously monitors changes in the dynamics of heart contractions. This article discusses the technical details of various solutions for detecting and responding to situations related to increased oxygen demand (e.g., exercise or stress) in implantable pacemakers, and reviews the results of clinical trials regarding the use of these algorithms.

show abstract

Section: Discussionmentioning

confidence: 99%