2024
DOI: 10.3389/fonc.2024.1389468
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Application and research progress of single cell sequencing technology in leukemia

Dan Xie,
Bangquan An,
Mingyue Yang
et al.

Abstract: Leukemia is a malignant tumor with high heterogeneity and a complex evolutionary process. It is difficult to resolve the heterogeneity and clonal evolution of leukemia cells by applying traditional bulk sequencing techniques, thus preventing a deep understanding of the mechanisms of leukemia development and the identification of potential therapeutic targets. However, with the development and application of single-cell sequencing technology, it is now possible to investigate the gene expression profile, mutati… Show more

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