2018
DOI: 10.1016/j.ijpharm.2017.08.021
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Application of a pH dependent taste-mask film coating for pediatric multiparticulate formulations

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“…Microencapsulation creates a physical barrier between the drug and the taste receptors in the form of a polymeric film thus leading to efficient taste masking. Although there are several ways to achieve microencapsulation, fluid bed processing is one of the most efficient, fast and economic techniques to achieve microcapsules with high yield, uniform coating and better entrapment efficiency leading to improved taste masking (Stange et al, 2014 ; Keser et al, 2018 ; Ghimire et al, 2018 ). In the present study, we sought to develop dry syrup formulation containing microencapsulated KCl which would not only mask the taste but also offer the advantages such as convenience of handling, lesser weight per container and overall better stability.…”
Section: Discussionmentioning
confidence: 99%
“…Microencapsulation creates a physical barrier between the drug and the taste receptors in the form of a polymeric film thus leading to efficient taste masking. Although there are several ways to achieve microencapsulation, fluid bed processing is one of the most efficient, fast and economic techniques to achieve microcapsules with high yield, uniform coating and better entrapment efficiency leading to improved taste masking (Stange et al, 2014 ; Keser et al, 2018 ; Ghimire et al, 2018 ). In the present study, we sought to develop dry syrup formulation containing microencapsulated KCl which would not only mask the taste but also offer the advantages such as convenience of handling, lesser weight per container and overall better stability.…”
Section: Discussionmentioning
confidence: 99%