The nursing profession is a profession that is prone to experiencing stress. Long work duration in accompanying patients is one of the factors that causes stress in nurses. To anticipate work-related stress problems, it is necessary to periodically identify the level of stress experienced by nurses. The use of mobile applications needs to be developed for easy and efficient stress assessment Android-based which are expected to help nurses identify the stress they are experiencing. The aim of this study was to developing a stress assessment application android-based to identify stress levels efficiently and effectively. This research uses design Research and Development (R&D) with a product development and validation approach through use trials on 34 nurses with a sampling method that is the total sample. Test use using the instrument System Usability Scale (SUS ). This research develops astress assessment application android-based , namely ENSS (Expanded Nursing Stress Scale) version 1.0 with features login, main menu of stress questionnaire and interpretation of filling results. Trial use by respondents received a score of 74.78 in the category Acceptable or acceptable. The ENSS application has been developed and is suitable for use in identifying stress levels in nurses.