The digital interface is crucial for nuclear plant operators, influencing their decision-making significantly. However, evaluations of these interfaces often overlook users’ decision-making performance; lack established standards, typically occurring after the design phase; and are unsuitable for large-scale assessments. Recognizing the vital role of interface information, this paper built on our previous research and proposed a method tailored for nuclear power plant interfaces, utilizing image entropy to evaluate the impact of information on decision-making. A comparative analysis with an experimental evaluation method empirically validated the effectiveness of the proposed method. This research offers a unique decision-making-centric method to interface evaluation, providing a standardized, adaptable framework for various design phases and enabling extensive and rapid evaluations.