Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering: a review

Prebiotic oligosaccharides change the concentrations of short-chain fatty acids and the microbial population of mouse bowel

“…Some indigestible oligosaccharides, such as galactooligosaccharides (GOS), fructooligosaccharides (FOS), mannanoligosaccharides (MOS), and chitooligosaccharides (COS), have been demonstrated to possess prebiotic activity in human (Campbell et Suh and Matthew, 2000;Zentek et al, 2002;Wu et al, 2005;Shoaf et al, 2006). FOS has been shown to be indigestible by human enzymes in the small intestine, but is extensively fermented in the large bowel (Mitsuoka et al, 1987) to SCFA, which can be absorbed and metabolized by the host.…”

Repair of articular cartilage defects in rabbits through tissue-engineered cartilage constructed with chitosan hydrogel and chondrocytes

“…It can also improve woundhealing in the connective tissues of several species (Kim et al, 2008). Furthermore, some characteristics of chitosan are similar to the extracellular matrix of articular cartilage, such as hyaluronic acid and glycosaminoglycan (GAG) (Francis Suh and Matthew, 2000). Alginate-chitosan microcapsules have been used to encapsulate mouse osteoblastic MC3T3-E1 cells (Qiao et al, 2014), and the results showed that the activity of cells in the alginate-chitosan microcapsules exceeded that of the alginate microcapsule group, which proved that chitosan has excellent biocompatibility.…”

Hydrogels from Chitosan and a Novel Copolymer Poly(<i>N</i>-Vinyl-2-Pyrrolidone-<i>Co</i>-Acrolein)

“…Throughout the last five decades numerous publications on this research topic have been released. Hydrogels play an important role in tissue engineering [2][3][4][5], dressings for burn wounds and other kinds of injuries [6,7], "intelligent" hidrogels for drug controlled release [8,9], and other biomedical applications [10].…”