Application of computational fluid dynamics for detection of high risk region in middle cerebral artery (MCA) aneurysm

Self Cite

The rupture of the aneurysm wall is highly associated with the hemodynamic feature of bloodstream as well as the geometrical feature of the aneurysm. Coiling is known as the most conventional technique for the treatment of intracranial cerebral aneurysms (ICA) in which blood stream is obstructed from entering the sac of the aneurysm. In this study, comprehensive efforts are done to disclose the impacts of the coiling technique on the aneurysm progress and risk of rupture. The computational fluid dynamic method is used for the analysis of the blood hemodynamics in the specific ICA. The impacts of the pulsatile blood stream on the high-risk region are also explained. Wall shear Stress (WSS) and Oscillatory shear index (OSI) factors are also compared in different blood viscosities and coiling conditions. According to our study, the hematocrit test (Hct) effect is evident (25% reduction in maximum WSS) in the two first stages (maximum acceleration and peak systolic). Our findings present that reduction of porosity from 0.89 to 0.79 would decrease maximum WSS by about 8% in both HCT conditions.

Section: Introductionmentioning

confidence: 99%

Computational study of the blood hemodynamic inside the cerebral double dome aneurysm filling with endovascular coiling

Rostamian

Fallah

Rostamiyan

et al. 2023

Self Cite

“…Understanding the relationship between aneurysm geometrical features and hemodynamic characteristics has become a subject of intense research in the field of vascular biomechanics 4 , 5 . Two key hemodynamic parameters that have been widely investigated are wall shear stress (WSS) and oscillatory shear index (OSI).…”

Section: Introductionmentioning

confidence: 99%

Impacts of morphology parameters on the risk of rupture in intracranial aneurysms: statistical and computational analyses

Wang,

Jin,

Chen

et al. 2023

The hemodynamic analysis of the blood stream inside the cerebral aneurysms reveals the risk of the aneurysm rupture. In addition, the high risk region prone to rupture would be determined by the hemodynamic analysis of the blood. In present article, computational fluid dynamic is used for the investigation of the hemodynamic effects on the aneurysm wall and risk of rupture. This study tries to find the connection between the risk of rupture with three geometrical features of aneurysm i.e., Ellipsoid Max semi-axis, Size ratio and Tortuosity. Statistical analysis is done over 30 different ruptured /unruptured ICA aneurysms to find meaningful relation between selected geometrical factors and rupture risk. The hemodynamic analysis is done over four distinct aneurysm models to attain more details on effects of chosen geometrical factors. The results of simulations indicate that the Ellipsoid Max semi-axis have meaningful impacts on the risk of rupture.

Section: Introductionmentioning

confidence: 99%

“…The formation and growth of the cerebral aneurysm is the mainly related to the blood rheology and characteristics. The early reports have shown that the blood flow features of Wall shear stress (WSS) and OSI have great impact on the rupture and bleeding of the cerebral aneurysms 3,4 .The advance in the computational techniques has enabled scientists to calculate this hemodynamics on the wall of the aneurysm 5,6 . Besides, technique of the magnetic resonance angiography (MRA) and computed tomography angiography (CTA) offer valuable information on the shape and feature of the real three-dimensional aneurysm which is essential for the computational modeling.…”

mentioning

confidence: 99%

Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study

Valipour

2022

One of common endovascular technique for treatment of MCA aneurysm is using coiling gel for limiting of blood stream. In this work, computational fluid dynamic is used for the simulation of the blood hemodynamic inside MCA in existence of coiling gel. This work has tried to visualize the impacts of blood characteristics i.e. hematocrit as a protein related factor on efficiency of coiling fiber inside the aneurysm. Tufts of polyester fibers may be attached to the coil to support thrombosis and platelet aggregation. Blood rheology analysis is done by solving RANS equations and it is assumed that blood stream is non-Newtonian with fluid–solid interaction. OSI and WSS are compared on sac surface area for different stages of blood cycle. Achieved results confirm that the coiling gel substantially decreases the blood circulation inside the aneurysm sac. It is also found that the influence of blood hematocrit decreases when the MCA aneurysm is filled by the coiling gel.