The problem encountered in the culture of asian redtail catfish is its slow growth. The increase in growth can be accelerated by the addition of bromealin enzymes found in pineapple processing industrial waste. The aim of this research was to analyze: the optimal dose of bromealin enzyme added to feed in increasing the activity of digestive enzymes and growth performance of asian redtail catchfish. The main ingredients used were asian redtail catchfish (Hemibagrus nemurus) measuring 5-7 cm, pakcoy plants, boster, bromealin enzymes, commercial pellets with 38% protein content, round tubs and gutters as test containers. The method of research used is Completely Randomized Design (CRD) experimental method with 1 factor, 5 levels of treatment and 3 replications. The treatment levels in this study were: without bromealin enzyme (P0), 2.5% kg-1 feed (P1), 3.5% kg-1 feed (P2), 4.5% kg-1 feed (P3) and 5.5% kg-1 feed (P4) respectively. To determine the effect of treatment, variance analysis (ANOVA) was performed using SPSS software version 13.0. The results showed that bromelin enzymes with different doses had an effect on digestive enzyme activity and growth performance of asian redtail catfish. The best treatment was found in the treatment of bromealin enzyme at 5.5 g kg-1 feed, which increased the protease enzyme by 95.56%, lipase 612.12%, amylase 338.12%, average growth weight of 13.85 grams, average growth length of 12.03 cm, absolute growth weight of 33.47 grams, absolute growth length 6.17 cm, specific growth rate of 2.92 %, Feed Efficiency of 69.33%, FCR of 1.45% and survival rates of 92.86% with water quality parameters such as temperature 24.33-29.73 °C, pH 6.17-7.67, dissolved oxygen (DO) 3.53-7.57 mg L-1, and ammonia 0.00537 mg L-1.