Application of Gas Chromatography to the Detection of tert-Amine Oxides.

Possible Antineoplastic Agents II

“…Preparation of Immunogen-The 3-hemisuccinyloxy derivative of clonazepam (11) was covalently coupled to bovine serum albumin using the mixed anhydride procedure of Erlanger et al (11). After successive dialysis against dioxane-water (l:l), 0.05 M borate buffer (pH 9), and water, the immunogen was isolated by lyophilization.…”

“…Synthesis of a few glutarimide analogs of the types 2phthalimidoglutarimide (thalidomide) (I) and 3-phenylglutarimide (11) and their biological evaluation in Ehrlich ascites carcinoma were reported previously (1). Meanwhile, more derivatives of I and I1 were synthesized and evaluated ugie, 9, l(1968 To whom inquiries should be directed.…”

Chemical Ionization Mass Spectra of Phenothiazine Derivatives and Their Oxygenated Analogs

“…Keyphrases Glutarimides, substituted-various derivatives synthesized, antineoplastic activity evaluated, mice Antineoplastic activity, potential-substituted glutarimides synthesized and screened, mice 0 Structure-activity relationships-various substituted glutarimides synthesized and screened for antineoplastic activity in mice Synthesis of a few glutarimide analogs of the types 2phthalimidoglutarimide (thalidomide) (I) and 3-phenylglutarimide (11) and their biological evaluation in Ehrlich ascites carcinoma were reported previously (1). Meanwhile, more derivatives of I and I1 were synthesized and evaluated ugie, 9, l(1968).…”