Application of orthogonal functions to spectrophotometric analysis: Determination of nifuroxime and furazolidone in pharmaceutical formulations

Hassan, Sayed M.; Elsayed, Laila; Kelani, Khadiga M.; Amer, M. M.

doi:10.1007/bf00487829

Cited by 7 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The orthogonal function method has been applied to the simultaneous determination of nifuroxime and furazolidone in pharmaceutical formulations. In this method, the correction of interference by either component is carried out using a calculated absorbance ratio at the absorption maxima (10).…”

Section: Introductionmentioning

confidence: 99%

Correction for Irrelevant Absorption in Multicomponent Spectrophotometric Assay of Riboflavin, Formylmethylflavin, and Degradation Products: Kinetic Applications

et al. 2013

View full text Add to dashboard Cite

Abstract. In the spectrophotometric assay of multicomponent systems involved in drug degradation studies, some minor or unknown degradation products may be present. These products may interfere in the assay and thus invalidate the results due to their absorption in the range of analytical wavelengths. This interference may be eliminated by the application of an appropriate correction procedure to obtain reliable data for kinetic treatment. The present study is based on the application of linear and non-linear irrelevant absorption corrections in the multicomponent spectrophotometric assay of riboflavin and formylmethylflavin during the photolysis and hydrolysis studies. The correction procedures take into account the interference caused by minor or unknown products and have shown considerable improvement in the assay data in terms of the molar balance. The treatment of the corrected data has led to more accurate kinetic results in degradation studies.

show abstract

Section: Introductionmentioning

confidence: 99%