The application of artificial intelligence technology not only realizes the transformation of people’s production and lifestyle but also promotes the transformation of the clothing industry. At present, the proportion of artificial intelligence in the clothing industry is becoming larger and larger. Using its advanced methods and technologies of information display and data analysis, this study is worth transforming and optimizing the clothing graphic design system under the artificial intelligence environment, so as to promote the intelligent development of the clothing industry. This study proposes to use three-dimensional image analysis algorithm technology to guide the integration of garment graphic design process and computer network, which is helpful to analyze and solve the imbalance between the singularity of traditional garment pattern design and people’s aesthetic appreciation at present. Using the technology and principle of artificial intelligence for reference, the intelligent clothing graphic design system is constructed and analyzed. In the analysis of the clothing graphic design system of a group, the group applied artificial intelligence technology to the customized clothing in the production workshop of the company. Although the efficiency of the adjustment system is not as good as that of mass production, it eliminates inventory, and its net profit can reach 20–30%, which is much higher than that of traditional clothing. In contrast, the industry reported a net profit of 12% of the highest level. Therefore, it is urgent to analyze the intelligent garment graphic design system through artificial intelligence technology.