Application of SSH and a macroarray to investigate altered gene expression in Mytilus edulis in response to exposure to benzo[a]pyrene

Reverse transcriptase activity in tissues of the soft shell clam Mya arenaria affected with haemic neoplasia

“…Agriculture in Prince Edward Island is dependent on pesticides (Mutch et al, 2002) which might affect clam population in North River. Consistent with this, Brown et al (2006) reported that gag-pol gene was up-regulated in digestive gland of M. edulis following exposure to benzo[a]pyrene.…”

Predicting growth and mortality of bivalve larvae using gene expression and supervised machine learning

“…For example, two ganglioside gm2 activator (GM2A) homologues (-a and -b in Table 4) were also associated with hyperlipidosis syndrome of chemically exposed adult mussels (Dondero et al, 2011). For example, the GM2A was induced in benzo[a]pyrene-treated adult mussels (Brown et al, 2006), involved in lipid metabolism in adult hypoxic oysters (Sussarellu et al, 2010) and nickel-or heat-stressed mussels (Mohamed et al, 2014). These GM2As were both oppositely expressed in 17β-Estradiol treated adult mussels (Canesi et al, 2004).…”

Bivalve Omics: State of the Art and Potential Applications for the Biomonitoring of Harmful Marine Compounds

“…galloprovincialis [81]. Gene expression profiling using microarray technologies is often carried out in these organisms by means of tailor-made microarray platforms [6,13,18,19,21,23,34,35,39,40,82,83,84,85,86,87,88,89]. RNA-Seq expression studies, on the other hand, are still hampered by the lack of reference genomes.…”

“…In fact, pioneer omic studies in bivalves were eminently based on transcriptomes, helping to set up the foundations for subsequent proteomic and genomic studies [18,19,20,21,22]. Metabolomic and epigenomic characterization of bivalves, on the other hand, still constitute emerging disciplines that would complete the necessary framework for integrative approaches (Figure 1).…”