For VR technology, the core goal is to create a sense of reality, so that users can not distinguish between the real world and virtual environment. The purpose of this paper is to study the application of artificial intelligence and VR technology in the display design of clothing stores. First of all, there are four ways of clothing display and display: filling display, eye-catching display, emphasizing display and close display. Secondly, the system structure of VR technology is divided into hardware equipment structure and key technical support. The design of artificial intelligence module and control instruction encryption are studied. Finally, the simulation of the display design environment of the clothing store by the follow-up system under the unfamiliar environment is carried out. The experimental results show that the delay time of 4G environment is shorter than that of WiFi environment. In the same network environment, generally speaking, the worse the quality of image compression, the shorter the delay time. As the quality of the compressed image becomes poor, the corresponding amount of data is also small, and the delay is also short. But the worse the quality of the compressed image is, the more computing resources are consumed, which will cause the delay of the device itself, and when the quality of the compressed image is 40, the delay time is not shorter than 60. The delay times of each test are only 1 to 2 times, and the actual delay time is only 2 seconds, which shows that the robot is more sensitive to the instructions.