Applications and perspectives on microfluidic technologies in ships and marine engineering: a review

Wang, Junsheng; Maw, Myint Myint; Yu, Xiaomei; Dai, Bowen; Wang, Ge; Jiang, Zong

doi:10.1007/s10404-017-1873-z

Cited by 20 publications

(10 citation statements)

References 102 publications

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“…These are complex devices with a network of fluid microchannels, valves, mixers, pumps, reaction chambers, and interconnected detectors, and they can perform many laborious procedures without manual intervention ( Jung et al, 2015 ). These features make the LOCs suitable for clinical diagnostic applications and immediate care tests ( Wang et al, 2017 ), allowing mass production at low cost. The LOC-based technology has been widely used for virus detection, and research has been published in the past, such as a comprehensive description of pathogen detection using microfluidic systems ( Mairhofer et al, 2009 ).…”

Section: Sars-cov-2 Detection In Wastewatermentioning

confidence: 99%

Review on the contamination of wastewater by COVID-19 virus: Impact and treatment

Lahrich

Laghrib

Farahi

et al. 2021

Science of The Total Environment

102

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Emerging viruses are a major public health problem. Most zoonotic pathogens originate in wildlife, including human immunodeficiency virus (HIV), influenza, Ebola, and coronavirus. Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus called SARS-associated coronavirus (SARS-CoV). Viruses are charged colloidal particles that have the ability to adsorb on surfaces depending on pH. Their sorptive interaction with solid particles has important implications for their behavior in aquatic environments, soils, sewage sludge, and other solid materials and their removal or concentration by water treatment processes. Current state of knowledge on the potential of wastewater surveillance to understand the COVID-19 pandemic is reviewed. This study also identified wastewater irrigation systems with a higher risk of COVID-19 transmission. Emphasis was placed on methodologies for the detection and quantification of SARS-CoV-2 in wastewater.

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Section: Sars-cov-2 Detection In Wastewatermentioning

confidence: 99%

Review on the contamination of wastewater by COVID-19 virus: Impact and treatment

Lahrich

Laghrib

Farahi

et al. 2021

Science of The Total Environment

102

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“…Each integrated LOC platform typically contains sets of microfluidic elements, each of which are dedicated to single operations such as reagent storage, fluid transport, fluid mixing, product detection, and possibly collection. These abilities make LOCs suitable for applications in clinical diagnostics as well as near-patient or point-of-care (POC) testing (Wang et al, 2017), potentially enabling low-cost mass production. These abilities make LOCs suitable for applications in clinical diagnostics as well as near-patient or point-of-care (POC) testing (Wang et al, 2017), potentially enabling low-cost mass production.…”

Section: Introductionmentioning

confidence: 99%

Recent advances in lab-on-a-chip technologies for viral diagnosis

Zhu

Fohlerová

Pekárek

et al. 2020

Biosensors and Bioelectronics

195

146

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A B S T R A C TThe global risk of viral disease outbreaks emphasizes the need for rapid, accurate, and sensitive detection techniques to speed up diagnostics allowing early intervention. An emerging field of microfluidics also known as the lab-on-a-chip (LOC) or micro total analysis system includes a wide range of diagnostic devices. This review briefly covers both conventional and microfluidics-based techniques for rapid viral detection. We first describe conventional detection methods such as cell culturing, immunofluorescence or enzyme-linked immunosorbent assay (ELISA), or reverse transcription polymerase chain reaction (RT-PCR). These methods often have limited speed, sensitivity, or specificity and are performed with typically bulky equipment. Here, we discuss some of the LOC technologies that can overcome these demerits, highlighting the latest advances in LOC devices for viral disease diagnosis. We also discuss the fabrication of LOC systems to produce devices for performing either individual steps or virus detection in samples with the sample to answer method. The complete system consists of sample preparation, and ELISA and RT-PCR for viral-antibody and nucleic acid detection, respectively. Finally, we formulate our opinions on these areas for the future development of LOC systems for viral diagnostics.

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“…Microfluidic chips or Lab‐on‐a‐chip (LOC) technologies provide an excellent platform for research on biochemical analyses in micro or nano scale size. There are many advantages such as fast detection, small size, low cost and easy operation, especially suitable for on‐site biochemical analyses in extreme conditions such as space and underwater environments . In recent years, various microfluidic chip technologies have been developed and showed remarkable potential for studying C. elegans .…”

Section: Introductionmentioning

confidence: 99%

A novel microfluidic capture and monitoring method for assessing physiological damage of C. elegans under microgravity

et al. 2019

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Spatial microgravity is a significant factor affecting and causing physiological changes of organisms in space environment. On‐site assessment of the damage associated to microgravity is very important for future long‐term space exploration of mankind. In this paper, a new microfluidic device for analyzing the damage of microgravity on Caenorhabditis elegans (C. elegans) has been developed. This device is mainly composed of a microfluidic chip, a dual imaging module, and an imaging acquisition and processing module, which are integrated into a compact system. The microfluidic chip is designed as a platform for monitoring C. elegans, which is captured in an imaging region through a suction structure in the microfluidic chip. A dual imaging module is designed to obtain the images of bright field and fluorescence of C. elegans. The behaviors of C. elegans are analyzed based on the dual‐mode imaging of bright field and fluorescence to assess the degree of damage due to microgravity. A comparative study using a commercial microscope is also conducted to demonstrate the unique advantage of the developed system under the simulated microgravity. The results show that the developed system can evaluate the damage of C. elegans under microgravity accurately and conveniently. Furthermore, this device has compact size and weight, easy operation, and low‐cost, which could be highly advantageous for on‐site evaluation of the damage to microorganisms under microgravity in a space station.

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Applications and perspectives on microfluidic technologies in ships and marine engineering: a review

Cited by 20 publications

References 102 publications

Review on the contamination of wastewater by COVID-19 virus: Impact and treatment

Review on the contamination of wastewater by COVID-19 virus: Impact and treatment

Recent advances in lab-on-a-chip technologies for viral diagnosis

A novel microfluidic capture and monitoring method for assessing physiological damage of C. elegans under microgravity

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