Applying a homogeneous pressure distribution to the upper vertebral endplate: Validation of a new loading system, pilot application to human vertebral bodies, and finite element predictions of DIC measured displacements and strains

Baleani, Massimiliano; Fraterrigo, Giulia; Erani, Paolo; Rota, Giulia; Berni, Matteo; Taddei, Fulvia; Schileo, Enrico

doi:10.1016/j.jmbbm.2023.105706

Cited by 1 publication

(1 citation statement)

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“…In recent studies, bone is most often represented as a linear elastic isotropic body [6][7][8]. Some authors take into account transverse isotropy [9], and studies can also be found in which bone tissue is modeled as a poroelastic body [10] or an elastoplastic continuum [11].…”

Section: Introductionmentioning

confidence: 99%

Modeling the Effect of Annulus Fibrosus Stiffness on the Stressed State of a Vertebral L1 Body and Nucleus Pulposus

Ardatov,

Pachaleva,

Aleksiuk

et al. 2024

Bioengineering

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The investigation examines the transference of stiffness from intervertebral discs (IVDs) to the lumbar body of the L1 vertebra and the interactions among adjacent tissues. A computational model of the vertebra was developed, considering parameters such as cortical bone thickness, trabecular bone elasticity, and the nonlinear response of the nucleus pulposus to external loading. A nonlinear dynamic analysis was performed, revealing certain trends: a heightened stiffness of the annulus fibrosus correlates with a significant reduction in the vertebral body’s ability to withstand external loading. At a supplied displacement of 6 mm, the vertebra with a degenerative disc reached its yielding point, whereas the vertebrae with a healthy annulus fibrosus exhibited a strength capacity exceeding 20%. The obtained findings and proposed methodology are potentially useful for biomedical engineers and clinical specialists in evaluating the condition of the annulus fibrosus and predicting its influence on the bone components of the spinal system.

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