Apport de l’élastographie en temps réel pour la caractérisation des masses testiculaires

Marsaud, A.; Durand, Mathieu; Raffaelli, Charles; Carpentier, Xavier; Rouscoff, Y.; Tibi, B.; Floch, Adrien; Villeneuve, Marie-Pierre; Haider, Romain; Fontas, Éric; Padovani, B.; Amiel, J.; Chevallier, D.

doi:10.1016/j.purol.2014.11.008

Cited by 18 publications

(6 citation statements)

References 13 publications

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“…Marsaud et al . found high sensitivity (96%) but low specificity (37.5%) for strain ratio (Marsaud et al ., 2015), while Pastore et al . suggested that strain ratio measurement may provide additional objective information to support the algorithm used to diagnose testicular lesions (Pastore et al ., 2014).…”

Section: Discussionmentioning

confidence: 99%

“…SE has been successfully used in the evaluation of acute scrotal pathology (Shah et al ., 2010; Patel et al ., 2014; Yusuf et al ., 2015). However, to date, only a few studies (Schurich et al ., 2009; Grasso et al ., 2010; Aigner et al ., 2012; Huang & Sidhu, 2012; Patel et al ., 2012; Marsaud et al ., 2015) and just one prospective study (Goddi et al ., 2012) have explored the role of SE in focal testicular lesions. Furthermore, only one retrospective study has assessed the value of strain ratio measurements in neoplastic testicular lesions (Pastore et al ., 2014).…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic value of qualitative and strain ratio elastography in the differential diagnosis of non‐palpable testicular lesions

et al. 2016

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SummaryThe purpose of this study was to evaluate prospectively the accuracy of qualitative and strain ratio elastography (SE) in the differential diagnosis of non‐palpable testicular lesions. The local review board approved the protocol and all patients gave their consent. One hundred and six patients with non‐palpable testicular lesions were consecutively enrolled. Baseline ultrasonography (US) and SE were correlated with clinical and histological features and ROC curves developed for diagnostic accuracy. The non‐palpable lesions were all ≤1.5 cm; 37/106 (34.9%) were malignant, 38 (35.9%) were benign, and 31 (29.2%) were non‐neoplastic. Independent risk factors for malignancy were as follows: size (OR 17.788; p = 0.002), microlithiasis (OR 17.673, p < 0.001), intralesional vascularization (OR 9.207, p = 0.006), and hypoechogenicity (OR, 11.509, p = 0.036). Baseline US had 89.2% sensitivity (95% CI 74.6–97.0) and 85.5% specificity (95% CI 75.0–92.8) in identifying malignancies, and 94.6% sensitivity (95% CI 86.9–98.5) and 87.1% specificity (95% CI 70.2–96.4) in discriminating neoplasms from non‐neoplastic lesions. An elasticity score (ES) of 3 out of 3 (ES3, maximum hardness) was recorded in 30/37 (81.1%) malignant lesions (p < 0.001). An intermediate score of 2 (ES2) was recorded in 19/38 (36.8%) benign neoplastic lesions and in 22/31 (71%) non‐neoplastic lesions (p = 0.005 and p = 0.001 vs. malignancies). None of the non‐neoplastic lesions scored ES3. Logistic regression analysis revealed a significant association between ES3 and malignancy (χ2 = 42.212, p < 0.001). ES1 and ES2 were predictors of benignity (p < 0.01). Overall, SE was 81.8% sensitive (95% CI 64.8–92.0) and 79.1% specific (95% CI 68.3–88.4) in identifying malignancies, and 58.6% sensitive (95% CI 46.7–69.9) and 100% specific (95% CI 88.8–100) in discriminating non‐neoplastic lesions. Strain ratio measurement did not improve the accuracy of qualitative elastography. Strain ratio measurement offers no improvement over elastographic qualitative assessment of testicular lesions; testicular SE may support conventional US in identifying non‐neoplastic lesions when findings are controversial, but its added value in clinical practice remains to be proven.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Diagnostic value of qualitative and strain ratio elastography in the differential diagnosis of non‐palpable testicular lesions

et al. 2016

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“…A handful of studies have investigated the ability of strain elastography to differentiate malignant neoplasms from benign neoplasms using VES and SR. Whilst hard elastograms, defined based on a VES of >3, demonstrate a high sensitivity (81.1%-100%) in differentiating malignant testicular neoplasms from benign lesions, the specificity varies considerably among studies (25%-98.2%) [2,4,10,19,22]. In a cohort containing 30 testicular neoplasms, Pastore et al [23] showed that SR provided adjunctive information about tumor characteristics along with B-mode and color Doppler imaging, aiding in the diagnosis of the neoplastic origin of testicular abnormalities.…”

Section: Testicular Neoplastic Lesionsmentioning

confidence: 99%

Elastography of focal testicular lesions: current concepts and utility

2019

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As a relatively new sonographic technique, tissue elastography has emerged as a qualitative and potentially quantitative adjunctive tool to provide additional information on tissue stiffness, aiming to further improve diagnostic confidence in discriminating benign from malignant focal testicular lesions. The purpose of this review is to provide an overview of the elastography techniques used to assess focal testicular lesions and their typical appearance on tissue elastography.

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“…SWE is an important method to demonstrate increased stiffness values affecting UDT volume and functions ( 24 , 36 , 37 , 38 ) . In our study, the average values for the healthy group were 1.47 (1.02–1.99) m/s.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic role of gray-scale and shear-wave elastography in pediatric patients with undescended testes: a prospective controlled study

Yurtsever,

Yıldız,

Amirjanov

et al. 2024

JUltrason

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Aim: Ultrasound elastography is a simple non-invasive method for measuring tissue elasticity in relation to tissue fibrosis. The aim of this study was to compare echogenicity, volume and shear wave velocities of undescended vs normally descended testes. Material and methods: Sixty-six boys with undescended testes were included in this study. The median age range was 35.5 (10–118) months old. The cases included in this prospective study consisted of 66 patients with non-operated undescended testes, with 51 of them being affected unilaterally and 15 affected bilaterally, as diagnosed by physical examination. The control group consisted of 31 healthy boys without any particular health problems. This prospective study was performed by gray-scale ultrasonography and shear wave elastography in boys with undescended testes and healthy testes. The testicular volumes were established by ultrasound measurement, the echogenicity and shear wave elastography values were measured in boys with unilateral and bilateral undescended testes, and the results were compared with healthy boys’ testes and their contralateral testes. The stiffness values were recorded for speed (m/s) and elasticity (kPa), and the stiffness values of undescended testes were compared with the healthy control group. Results: Echogenicity values were lower in the bilateral undescended testes group than in the healthy group, and the healthy group’s echogenicity was normal (p <0.001). The ROC curve was used to identify a cut-off shear wave elastography value for predicting decreased testicular echogenicity by using average shear wave elastography values. The area under the curve for the undescended testes was 0.78 (95% CI: 0.70–0.85, sensitivity 83.7%, specificity 68.7%, p <0.001), with an average shear wave elastography value of 2.32 (m/s) for above the cut-off point indicates. This was found to be significantly associated with reduced echogenicity on gray-scale ultrasonography, suggesting that it may be correlated with fibrosis developing in patients with undescended testes. Conclusion: The study provides interesting findings in that it proposes an alternative non-invasive method for the assessment of testicular tissue in undescended testes. We used shear wave elastography to compare the stiffness of normal testes in both heathy patients and in the contralateral healthy testes of boys with undescended testes, with the values obtained for the undescended testes reflecting the level of fibrosis of the parenchyma. Another outcome of this study was observed in patients with unilateral undescended testes, where the normally descended testes showed increased shear wave elastography values, which could be an early indication of parenchymal change.

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Apport de l’élastographie en temps réel pour la caractérisation des masses testiculaires

Cited by 18 publications

References 13 publications

Diagnostic value of qualitative and strain ratio elastography in the differential diagnosis of non‐palpable testicular lesions

Diagnostic value of qualitative and strain ratio elastography in the differential diagnosis of non‐palpable testicular lesions

Elastography of focal testicular lesions: current concepts and utility

Diagnostic role of gray-scale and shear-wave elastography in pediatric patients with undescended testes: a prospective controlled study

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