Approaches for network based drug discovery

Abstract

Introduction 3. Interaction of drug with target 4. Methods to study drug interaction 4.1 Molecular docking-based method 4.2 Pharmacophore-based method 4.3 Similarity-based method 4.4 Machine learning-based 4.5 Network based methods 5. Drug repositioning 6. Data sources for network construction 7. Side effects nbdd analysis 8. Drug discovery from medicinal plants by nbdds 9. Elucidation of molecular mechanisms by nbdds 10. Protein-protein interaction (PPI) networks 10.1 Analyses of PPI network 10.2 PPI characterization by in silico approaches 11. Integrated network-based methods 12. Conclusions 13. Ethics approval and consent to participate 14. Author contributions 15. Acknowledgment 16. Funding 17. Conflict of interest 18. References