APTA Cross Sections and Academies Recommendations for COVID-19 Core Outcome Measures

Wells, Chris; Kegelmeyer, Deb; Mayer, Kirby P.; Kumble, Sowmya; Reilley, Anne; Campbell, Angela; Martin, Rebecca

doi:10.1097/jat.0000000000000172

Cited by 4 publications

(7 citation statements)

References 67 publications

(87 reference statements)

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“…The SPPB has been identified in the regression analysis as the only measure to reflect quality of life. Considering the practicability of SPPB, our results support the previous statements describing it as one of the simple and affordable tools 14,31,60 …”

Section: Discussionsupporting

confidence: 87%

“…Considering the practicability of SPPB, our results support the previous statements describing it as one of the simple and affordable tools. 14,31,60 Our research presents one of the very few scientific studies on post-COVID-19 patients describing the level of functional status and quality of life 2-3 weeks following hospital discharge. However, our study has a few limitations.…”

Section: Regression Analysismentioning

confidence: 99%

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Functional status and quality of life in post‐COVID‐19 patients two to three weeks after hospitalization: A cross‐sectional study

Qorolli,

Beqaj,

Ibrahimi‐Kaçuri

et al. 2023

Health Science Reports

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Background and AimsExtended hospitalization due to coronavirus disease 2019 (COVID‐19) is associated with residual musculoskeletal and functional deficits lasting even 6 months after discharge; therefore, it is crucial that post‐hospitalized patients are promptly assessed. The aim of this study was to identify post‐COVID‐19 patients' functional status and quality of life, as well as to investigate their inter‐relatedness 2–3 weeks after hospital discharge.MethodsThe study included 39 post‐COVID‐19 patients previously hospitalized in the Clinic for Infectious Diseases at the University Clinical Center of Kosovo (UCCK) from August to December 2021. Physiotherapeutic assessment encompassed socio‐demographic and clinical data including Short Physical Performance Battery (SPPB) for physical functional performance, hand grip strength, 6‐min Walk Test (6MWT) for aerobic capacity and endurance, EuroQol 5‐Dimension 5‐Level (EQ‐5D‐5L) for quality of life, Visual Analogue Scale (VAS) for pain, Borg CR10 for dyspnea, peripheral oxygen saturation and heart rate. Descriptive statistics, Pearson correlation, and multiple linear regression analysis were utilized for data processing.ResultsThe median (interquartile range [IQR]) for Borg CR10, VAS pain scale, total SPPB, grip strength, and 6MWT were 1 (0–3), 3 (1–6), 9 (8–10), 30.5 (23.2–43.5) kg, 344.5 (312.7–381.7) m respectively, while the mean (SD) for EQ‐5D‐5L index value was 0.7 (0.2). The strongest and most significant correlation was depicted between SPPB total score and its subscales, followed by correlation with EQ‐5D‐5L (r = 0.719, p < 0.001), grip strength (r = 0.612 p < 0.001), Borg CR10 (r = −0.515, p = 0.001), 6MWT (r = 0.416, p = 0.02), and VAS scale (r = −0.343, p = 0.03). Using the multiple regression analysis, the grip strength, Borg‐CR10, and 6MWT were found to be strongly predictive of SPPB total score.ConclusionIn post‐COVID‐19 patients' functional status and quality of life were impaired 2–3 weeks following hospitalization. SPPB showed the most frequent and significant correlation with other variables, hence it should be considered as one of the primary screening tools.

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Section: Discussionsupporting

confidence: 87%

Section: Regression Analysismentioning

confidence: 99%

Functional status and quality of life in post‐COVID‐19 patients two to three weeks after hospitalization: A cross‐sectional study

Qorolli,

Beqaj,

Ibrahimi‐Kaçuri

et al. 2023

Health Science Reports

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“…The 6MWT, which measures the distance covered over a time of 6 min, was recommended by KNGF guidelines [ 26 ], considering the requirement for larger space to conduct the test. The American Physical Therapy Association recommended the 2-minute step test [ 30 ] as a COVID-19 core outcome measure for endurance [ 31 ].…”

Section: Methods Used To Evaluate the Physical And Functional Outcome...mentioning

confidence: 99%

“…The most frequently used outcome measures for functional mobility and balance are the Short Physical Performance Battery (SPPB) [ 32 ] and Tinetti balance test [ 33 , 34 ]. The SPPB is recommended as a core measure of functional mobility allowing the assessment of gait speed, balance ability, and a 5 times sit-to-stand performance in 10 min [ 26 , 31 ]. It is preferred that muscle strength is objectively evaluated using dynamometry [ 35 ].…”

Section: Methods Used To Evaluate the Physical And Functional Outcome...mentioning

confidence: 99%

“…For assessment of quality of life and cognitive and emotional state, the EQ-5D-5L [ 45 , 46 ] and the 36-Item Short Form Survey (SF-36) [ 47 ] are most utilized. EQ-5D-5L is recommended as a core outcome measure for assessment of health-related quality of life, along with PROMIS-Global-10, which was adapted from SF-36 and EQ-5D [ 31 , 48 ]. Additionally, in clinical practice, the Feeling Thermometer (FT) [ 49 ], the Hospital Anxiety and Depression scale (HADS) [ 50 ], the Generalized Anxiety Disorder-7 (GAD-7) score [ 51 ], and the Patient Health Questionnaire (PHQ-9) [ 52 ] are often used.…”

Section: Methods Used To Evaluate Quality Of Life Following Physiothe...mentioning

confidence: 99%

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Effects of Physiotherapy on Rehabilitation and Quality of Life in Patients Hospitalized for COVID-19: A Review of Findings from Key Studies Published 2020-2022

et al. 2022

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The estimated percentage of individuals with COVID-19 due to infection with SARS-CoV-2 in need of hospitalization mostly increases proportionally with age, reaching almost 10% for those older than 60 years. Among hospitalized patients, one-fifth require treatment in the intensive care unit (ICU) due to acute respiratory distress syndrome, multiorgan failure, or hypoxemic respiratory insufficiency. Patients with moderate and severe COVID-19 who were hospitalized during the early stages of the pandemic and who continue to be hospitalized report fatigue, muscle weakness, joint stiffness, reduced mobility, increased risk of falls, and impaired quality of life. Physiotherapy is recognized to be important in the rehabilitation of COVID-19 patients requiring hospitalization. The current physiotherapy guidelines and recommendations for individuals with COVID-19, which include treatment methods and outcome measures for evaluation of the effects on respiratory and physical function and quality of life, are those established from the pre-COVID-19 era. The available extant scientific literature mainly reported the effect of physiotherapy in patients with COVID-19 in the acute, hospitalization courses of the disease, while there is a lack of quality primary, experimental studies on the effects of physiotherapy in rehabilitation of post-COVID-19 patients after hospitalization. This review aims to present an update on the effects of physiotherapy on rehabilitation and quality of life in patients hospitalized for COVID-19 and the findings from key studies published between 2020 and 2022.

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Physical Therapy Outcome Measures Used in Persons With Long Covid: A Systematic Review of Interventional Studies Up to 1-Year Postglobal Health Emergency

Lopes Sauers,

Johnson,

Mortensen

et al. 2024

Cardiopulm Phys Ther J

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Purpose: To identify the most frequently used outcome measures in interventional studies for Long Covid in outpatient, home-based, and telerehabilitation physical therapy settings. Methods: Registered in PROSPERO (registration number: CRD42021286714) and conducted according to PRISMA guidelines, this review included interventional studies performed in outpatient, telerehabilitation, or home-based physical therapy settings, assessing adults with persistent Long Covid symptoms in at least 3 months post-COVID-19 infection and published in English, Spanish, or Portuguese. A comprehensive search strategy was executed across PubMed, Embase, Scopus, PEDro, SciELO, Web of Science, and CINAHL. Data were managed via Covidence, with studies independently screened and extracted by multiple authors. The risk of bias was assessed using the National Heart, Lung, and Blood Institute (NHLBI) quality assessment tool. Outcome measures were mapped to constructs based on core outcome sets (COS) for Long Covid by an international Delphi consensus and American Physical Therapy Association Cross Sections and Academies for COVID-19. The frequency of use of each outcome measure, between-group comparisons, clinical meaningfulness, and reference values from previous studies were reported. Results: Fourteen studies met the inclusion criteria, utilizing 43 distinct outcome measures to assess constructs such as health-related quality of life, functional mobility, endurance, cognition, mental health, strength/power, and fatigue. Notably, 76.4% (33/43) of these measures were used in only one study, with the EQ-5D being the most frequently employed (50%, 7/14). Conclusions: While the outcome measures largely aligned with recommended core domains for Long Covid, significant heterogeneity was observed. Given the variability in outcome measures, the EQ-5D is recommended for assessing health-related quality of life in individuals with Long Covid.

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APTA Cross Sections and Academies Recommendations for COVID-19 Core Outcome Measures

Cited by 4 publications

References 67 publications

Functional status and quality of life in post‐COVID‐19 patients two to three weeks after hospitalization: A cross‐sectional study

Functional status and quality of life in post‐COVID‐19 patients two to three weeks after hospitalization: A cross‐sectional study

Effects of Physiotherapy on Rehabilitation and Quality of Life in Patients Hospitalized for COVID-19: A Review of Findings from Key Studies Published 2020-2022

Physical Therapy Outcome Measures Used in Persons With Long Covid: A Systematic Review of Interventional Studies Up to 1-Year Postglobal Health Emergency

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