Aptamer modified MoS2 nanosheets application in targeted photothermal therapy for breast cancer

Pang, Bo; Yang, Huiru; Wang, Liying; Chen, Jiaqi; Jin, Lihong; Shen, Bingjun

doi:10.1016/j.colsurfa.2020.125506

Cited by 23 publications

(9 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A study conducted by Pang and team has proven a good cytotoxicity index with favorable safety level while identifying tumor cells using a derivative of molybdenum disulfide nanomaterial. 206 Another study by Yin and team shows that the low cytotoxicity of molybdenum disulfide nanosheet is not capable of rupturing the cell membrane to induce a cell death. 207 Thus, molybdenum disulfide is an excellent agent for many biological applications.…”

Section: Molybdenum Disulfide For Pttmentioning

confidence: 99%

“…Multiple research projects have proven molybdenum disulfide to have low cytotoxicity. A study conducted by Pang and team has proven a good cytotoxicity index with favorable safety level while identifying tumor cells using a derivative of molybdenum disulfide nanomaterial . Another study by Yin and team shows that the low cytotoxicity of molybdenum disulfide nanosheet is not capable of rupturing the cell membrane to induce a cell death .…”

Section: Molybdenum Disulfide For Pttmentioning

confidence: 99%

See 1 more Smart Citation

Potential and Progress of 2D Materials in Photomedicine for Cancer Treatment

Bhatt

Pena-Zacarias

Beaven

et al. 2023

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

Over the last decades, photomedicine has made a significant impact and progress in treating superficial cancer. With tremendous efforts many of the technologies have entered clinical trials. Photothermal agents (PTAs) have been considered as emerging candidates for accelerating the outcome from photomedicine based cancer treatment. Besides various inorganic and organic candidates, 2D materials such as graphene, boron nitride, and molybdenum disulfide have shown significant potential for photothermal therapy (PTT). The properties such as high surface area to volume, biocompatibility, stability in physiological media, ease of synthesis and functionalization, and high photothermal conversion efficiency have made 2D nanomaterials wonderful candidates for PTT to treat cancer. The targeting or localized activation could be achieved when PTT is combined with chemotherapies, immunotherapies, or photodynamic therapy (PDT) to provide better outcomes with fewer side effects. Though significant development has been made in the field of phototherapeutic drugs, several challenges have restricted the use of PTT in clinical use and hence they have not yet been tested in large clinical trials. In this review, we attempted to discuss the progress, properties, applications, and challenges of 2D materials in the field of PTT and their application in photomedicine.

show abstract

Section: Molybdenum Disulfide For Pttmentioning

confidence: 99%

Section: Molybdenum Disulfide For Pttmentioning

confidence: 99%

Potential and Progress of 2D Materials in Photomedicine for Cancer Treatment

Bhatt

Pena-Zacarias

Beaven

et al. 2023

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

show abstract

“…However, its ability to recognize specific tumor cells needs to be improved. For example, Pang et al developed a new method [ 73 ] which used MoS 2 as the photothermal agent. Firstly, by mixing MoS 2 and bovine serum albumin (BSA), researchers obtained MoS 2 -BSA nanosheets.…”

Section: Aptamer-bound Nanomaterials Used In Different Cancer Therapiesmentioning

confidence: 99%

Applications of Aptamer-Bound Nanomaterials in Cancer Therapy

et al. 2021

View full text Add to dashboard Cite

Cancer is still a major disease that threatens human life. Although traditional cancer treatment methods are widely used, they still have many disadvantages. Aptamers, owing to their small size, low toxicity, good specificity, and excellent biocompatibility, have been widely applied in biomedical areas. Therefore, the combination of nanomaterials with aptamers offers a new method for cancer treatment. First, we briefly introduce the situation of cancer treatment and aptamers. Then, we discuss the application of aptamers in breast cancer treatment, lung cancer treatment, and other cancer treatment methods. Finally, perspectives on challenges and future applications of aptamers in cancer therapy are discussed.

show abstract

“…As shown in Figure 1, the classification of PTAs can be broadly divided into inorganic PTAs and organic PTAs. Among them, inorganic PTAs mainly include noble metal nanoparticles (gold nanorods, 36–38 gold nanocrystals, 39 gold nanostars, 40 gold nanoshells 41,42 ), carbon nanomaterials (graphene, 43 carbon nanotubes 44,45 ), and other inorganic nanoparticles (black phosphorous, 46,47 MoS 2 48–50 and silica, 51 and so on). Organic materials include organic dyes (indocyanine green [ICG], 52 Prussian blue 53 ) and polymer nanoparticles (such as polypyrrole, 54,55 semiconducting polymer nanoparticles 56 ).…”

Section: Introductionmentioning

confidence: 99%

Biomedical applications and prospects of temperature‐orchestrated photothermal therapy

Zhang

et al. 2022

MedComm – Biomaterials and Applications

View full text Add to dashboard Cite

Photothermal therapy (PTT) has been regarded as a promising strategy considering its advantages of high inherent specificity and a lower invasive burden. Since the photothermal killing of cells/bacteria showed different patterns of death depending on the varying temperature in PTT, the temperature change of PTT is vital to cell/tissue response in scientific research and clinical application. On one hand, mild PTT has received substantial attention in the treatment of cancer and soft/hard tissue repair. On the other hand, the high temperature induced by PTT is capable of antibacterial capacity, which is better than conventional antibiotic therapy with drug resistance. Herein, we summarize the recent developments in the application of temperature-dependent photothermal biomaterials, mainly covering the temperature ranges of 40-42°C, 43-50°C, and over 50°C. We highlight the biological mechanism of PTT and the latest progress in the treatment of different diseases. Finally, we conclude by discussing the challenges and perspectives of biomaterials in addressing temperatureorchestrated PTT. Given a deep understanding of the interaction between temperature and biology, rationally designed biomaterials with sophisticated photothermal responsiveness will benefit the outcomes of personalized PTT toward various diseases.

show abstract

Aptamer modified MoS2 nanosheets application in targeted photothermal therapy for breast cancer

Cited by 23 publications

References 31 publications

Potential and Progress of 2D Materials in Photomedicine for Cancer Treatment

Potential and Progress of 2D Materials in Photomedicine for Cancer Treatment

Applications of Aptamer-Bound Nanomaterials in Cancer Therapy

Biomedical applications and prospects of temperature‐orchestrated photothermal therapy

Contact Info

Product

Resources

About