Aqueous two‐phase systems in Latin America: perspective and future trends

Abstract

Aqueous two‐phase systems (ATPS) have been demonstrated to be a simple and robust worldwide applied bioprocessing technology. From high value microscopic to macroscopic biological molecules obtained from a wide broad of matrices, ATPS have shown a high efficiency capacity for their concentration, enrichment, recovery, and purification. Particularly in Latin America, four relevant countries have paved the way and played important leading roles in this transformation history. This perspective article aims to present a critical analysis of the practical evolution of the main implementations of ATPS in Argentina, Brazil, Chile, and Mexico. Special attention is given to novel applications of this biphasic bioprocess that are being explored to accomplish visionary therapeutic tasks for the healthcare, biotechnology, and pharmaceutical sectors, as well as other environmental purposes. © 2021 Society of Chemical Industry (SCI).

Theoretical Aspects and Applications of Aqueous Two‐Phase Systems

“…1). Several books and review papers have been published on these applications [1,4,[9][10][11][12]. ATPE offers high capacity, low interfacial tension, good yield, high selectivity, shorter processing time and energy, and ease of scaling.…”

Special Issue: biotechnology advances in Latin America

“…The Special Issue starts with a perspective article, 1 in which professor Marco Rito-Palomares together with an international team presents a critical analysis of the evolution of the main implementations of aqueous two-phase systems in Argentina, Brazil, Chile, and Mexico. Two review papers are also included, the first one by Sarmiento-Padilla et al 2 is about circular bioeconomy in the production of fucoxanthin from aquatic biomass addressing extraction methodologies, applications and challenges in this field.…”