Arbonematodes – Nematode Infections Transmissible by Arthropods

doi:10.1159/000345752

Cited by 6 publications

(3 citation statements)

References 71 publications

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“…To understand the mechanism by which avermectin acts against different species of insects, arthropods, nematodes and immature worms such as flukes, tapeworms and filarial worms, couples with good tolerance by the host animals. It is necessary to isolate the binding site of avermectin in various species and study how it induces the opening of chloride channels and increases hyperpolarization, since it has been established that its binding site is specific to other effector molecules [ 61 ].…”

Section: Avermectin Derivatives Formulations Therapeutic and Toxmentioning

confidence: 99%

Avermectin Derivatives, Pharmacokinetics, Therapeutic and Toxic Dosages, Mechanism of Action, and Their Biological Effects

et al. 2020

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Avermectins are a group of drugs that occurs naturally as a product of fermenting Streptomyces avermitilis, an actinomycetes, isolated from the soil. Eight different structures, including ivermectin, abamectin, doramectin, eprinomectin, moxidectin, and selamectin, were isolated and divided into four major components (A1a, A2a, B1a and B2a) and four minor components (A1b, A2b, B1b, and B2b). Avermectins are generally used as a pesticide for the treatment of pests and parasitic worms as a result of their anthelmintic and insecticidal properties. Additionally, they possess anticancer, anti-diabetic, antiviral, antifungal, and are used for treatment of several metabolic disorders. Avermectin generally works by preventing the transmission of electrical impulse in the muscle and nerves of invertebrates, by amplifying the glutamate effects on the invertebrates-specific gated chloride channel. Avermectin has unwanted effects or reactions, especially when administered indiscriminately, which include respiratory failure, hypotension, and coma. The current review examines the mechanism of actions, biosynthesis, safety, pharmacokinetics, biological toxicity and activities of avermectins.

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Section: Avermectin Derivatives Formulations Therapeutic and Toxmentioning

confidence: 99%

Avermectin Derivatives, Pharmacokinetics, Therapeutic and Toxic Dosages, Mechanism of Action, and Their Biological Effects

et al. 2020

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“…(Intarapuk and Bhumiratana 2021). This worm is transmitted by vector insects of the mosquitoes, especially Culex (Blut 2013). There are more than 38 species of mosquitoes that act as vectors of filariasis transmission (Famakinde 2018), including Culex quinquefasciatus (Simonsen and Mwakitalu 2013;Susilowati 2018), Culex vishnui (Nchoutpouen et al 2019), Mansonia africana and Mansonia unifo (Ughasi et al 2012).…”

Section: Introductionmentioning

confidence: 99%

First report of entomopathogenic fungi from South Sumatra (Indonesia): pathogenicity to egg, larvae, and adult of Culex quinquefasciatus

et al. 2022

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Abstract. Ramayanti I, Herlinda S, Muslim A, Hasyim H. 2022. First report of entomopathogenic fungi from South Sumatra (Indonesia): pathogenicity to egg, larvae, and adult of Culex quinquefasciatus. Biodiversitas 23: 5695-5702. Mosquito control has currently used many biocontrol agents, such as entomopathogenic fungi. So, the study aimed to determine the pathogenicity of the entomopathogenic fungi from South Sumatra to the eggs, larvae, and adults of Culex quinquefasciatus. The fungal isolates used were eight isolates from South Sumatra and have been identified molecularly. The fungal species that were the most pathogenic to the eggs of Cx. quinquefasciatus were Beauveria bassiana (BSwTd4, TaLmME, TaPsBA isolates), Metarhizium anisopliae (MSwTp3 isolate), Penicillium citrinum (BKbTp isolate), and Talaromyces diversus (MSwTp1 isolate). The Cx. quinquefasciatus eggs infected with the fungus not only could kill the eggs but also could continue to kill the emerging larvae, pupae, and adult. This is the first record that B. bassiana, M. anisopliae, P. citrinum, and T. diversus from South Sumatera Indonesia were pathogenic to the eggs of Cx. quinquefasciatus and had ovicidal activity. The most pathogenic fungal species to the larvae of Cx. quinquefasciatus were M. anisopliae (MSwTp3 isolate) and B. bassiana (BSwTd4 and TaLmME isolates). Three species of entomopathogenic fungi that were the most pathogenic to the adults of Cx. quinquefasciatus were M. anisopliae (MSwTp3 isolate), B. bassiana (BSwTd4 and TaLmME isolates), and P. citrinum (BKbTp isolate). Finally, The entomopathogenic fungi from South Sumatra have the negative effect on Cx. quinquefasciatus growth. The entomopathogenic fungi from South Sumatra have potential to be developed as the ovicide, larvicide, and adulticide. The future application of the fungi against the mosquito eggs, larvae, and adults can be used an ovitrap, fungal spores formulated in a synthetic oil, and fungus-impregnated black cloths, respectively.

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“…Filariasis remains a health concern in endemic regions [ 5 , 6 ]. The infection is mostly asymptomatic.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 unfolding filariasis: The first case of SARS-CoV-2 and Wuchereria bancrofti coinfection

Mohamed

Yousaf

et al. 2020

PLoS Negl Trop Dis

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With the evolution of the Coronavirus Disease 2019 (COVID-19) pandemic, the number of patients brought to medical attention has increased. This has led to the unmasking of many coexisting occult infections and comorbidities such as tuberculosis, dengue, human immunodeficiency viral infection, diabetes, and hypertension. We report the first case of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, unveiling the diagnosis of asymptomatic filariasis. A 37-year-old gentleman presented with shortness of breath, fever, and cough. He was found to have COVID-19 pneumonia. During his stay, microfilaria of Wuchereria bancrofti was detected incidentally on a blood smear exam. Consequently, the patient received appropriate treatment for both conditions. In order not to miss relevant concomitant diagnoses, it is prudent to keep a broad differential diagnosis when faced with SARS-CoV-2–infected patients; this is especially true when atypical symptoms are present or in areas endemic with other infections.

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Arbonematodes – Nematode Infections Transmissible by Arthropods

Cited by 6 publications

References 71 publications

Avermectin Derivatives, Pharmacokinetics, Therapeutic and Toxic Dosages, Mechanism of Action, and Their Biological Effects

Avermectin Derivatives, Pharmacokinetics, Therapeutic and Toxic Dosages, Mechanism of Action, and Their Biological Effects

First report of entomopathogenic fungi from South Sumatra (Indonesia): pathogenicity to egg, larvae, and adult of Culex quinquefasciatus

COVID-19 unfolding filariasis: The first case of SARS-CoV-2 and Wuchereria bancrofti coinfection

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