Are diuretics effective for Ménière`s disease?

Rosenbaum, Andrés; Winter, Matías

doi:10.5867/medwave.2018.02.7187

Cited by 13 publications

(6 citation statements)

References 12 publications

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“…Diuretics have also been recommended to control vertigo attacks in MD, due to their effects in reducing the endolymphatic pressure and volume. As for steroids and gentamicin, there are no high-quality data demonstrating the efficacy of oral diuretic therapy 30 ; in addition, a meta-analysis from Rosenbaum and Winter 31 concluded that it is not clear if diuretic lead to a symptomatic improvement of vertigo.…”

Section: Discussionmentioning

confidence: 99%

Pharmacological, surgical and diagnostic innovations in Meniere’s disease: a review

Scarpa

Ralli²,

Bonis

et al. 2020

Translational Medicine @ UniSa

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Meniere's disease is an inner ear disorder characterized by the presence of endolymphatic hydrops in the inner ear and symptomatology of recurrent and debilitating vertigo attacks, tinnitus, aural fullness, and fluctuating sensorineural hearing loss. Although many therapeutic options for MD have been proposed during years, no consensus has been reached by the scientific community. In the last decade, many therapeutic options have been proposed, as intratympanic steroid, intratympanic gentamicin, and intravenous glycerol. Recently, the role of the antisecretory factor in the diet of MD patients have been investigated. Surgery is recommended for intractable MD; some authors proposed new approaches including transcanal endoscopic infracochlear vestibular neurectomy, new marsupiliazation technique in sac surgery, and tenotomy of the stapedius and tensor tympani muscles.

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Section: Discussionmentioning

confidence: 99%

Pharmacological, surgical and diagnostic innovations in Meniere’s disease: a review

Scarpa

Ralli²,

Bonis

et al. 2020

Translational Medicine @ UniSa

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“…Rosenbaum, however, discussed the potential that a sudden drop in blood pressure caused by diuretics could result in a negative sympathetic response and provide the cochlear vasopressin receptors false information. This would eventually result in permanent inner ear damage (Rosenbaum and Winter, 2018;Crowson et al, 2016).…”

Section: Diureticsmentioning

confidence: 99%

A Review on Management of Meniere’s Disease with Unani Medicine

et al. 2023

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Meniere’s disease, also called endolymphatic hydrops, is a disorder of the inner ear where the endolymphatic system is distended due to endolymph. It is characterized by vertigo, tinnitus, sensorineural hearing loss, and aural fullness. Meniere's disease's primary pathology disease is the distension of the endolymphatic system due to an increased volume of endolymph. This can result either from increased production of endolymph or its faulty absorption or both. The description of hypothyroidism as a disease is not directly found in Unani texts. However, in Unani medicine, the signs and symptoms of Meniere's disease such as Dawar (vertigo), Taneen (tinnitus), Hissi Asabi Bahrapan (sensorineural hearing loss), and Seqal-e-Uzn (aural fullness) were linked to clinical manifestation in the context of Su-e-Mizaj Barid Maddi (derangement in cold temperament) as a result of excessive production of endolymph. On the basis of this fact, an attempt has been understanding the illness and how Unani Medicine treats it is provided.

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“…En términos farmacológicos, los diuréticos representan el tratamiento de primera elección para disminuir el volumen y la presión endolinfática 13 .…”

Section: Primer Escalónunclassified

Enfermedad de Meniere: un vértigo de causa compleja

Ruiz-Xiao,

Morales-Roldán,

Soto-Blanco

2023

Rev Hisp Cienc Salud

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La Enfermedad de Ménière (EM) es una afección rara del oído interno que provoca vértigo, hipoacusia neurosensorial y acúfenos. Aunque su origen exacto sigue siendo enigmático, se ha vinculado con hidropesía endolinfática, un exceso de endolinfa en el oído interno. Un componente genético autosómico dominante se ha observado en alrededor del 10% de los casos. El diagnóstico se establece en base a criterios clínicos, diferenciando entre EM definitiva y probable. Para nuevos pacientes, se sugiere un enfoque conservador inicial que podría incluir cambios en el estilo de vida y dieta. El tratamiento farmacológico, como betahistidina, diuréticos y terapias intratimpánicas, es una opción. En casos extremos, la cirugía es considerada. A pesar de sus desafíos, una comprensión multidisciplinaria es crucial para abordar esta compleja afección.

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Are diuretics effective for Ménière`s disease?

Cited by 13 publications

References 12 publications

Pharmacological, surgical and diagnostic innovations in Meniere’s disease: a review

Pharmacological, surgical and diagnostic innovations in Meniere’s disease: a review

A Review on Management of Meniere’s Disease with Unani Medicine

Enfermedad de Meniere: un vértigo de causa compleja

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