2017
DOI: 10.1001/jamapsychiatry.2017.1054
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Are There Differences in Disruptions of Reward Processing Between Substance Use Disorder and Gambling Disorder?—Reply

Abstract: In Reply Fogelson and Leuchter have responded to our proposed staging scheme for treatment-resistant depression (TRD) published in JAMA Psychiatry. 1 We do not fundamentally disagree with their arguments; however, we stand by our proposal that psychiatry needs to move toward a more empirically based TRD definition.Fogelson and Leuchter express concern about the lack of evidence to support using different antidepressant classes to improve antidepressant efficacy. In putting forward our preliminary TRD staging … Show more

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“…We also note that in our process of parcellating four regions within the DMN, our clusters had become relatively small, which may have limited our ability to find differences between cluster-topic associations among each DMN node. Future work may be able to address this limitation by using image-based meta analyses 90 , 91 , which may be possible as more researchers heed calls to share unthresholded statistical maps 82 , 89 , 92 .…”
Section: Discussionmentioning
confidence: 99%
“…We also note that in our process of parcellating four regions within the DMN, our clusters had become relatively small, which may have limited our ability to find differences between cluster-topic associations among each DMN node. Future work may be able to address this limitation by using image-based meta analyses 90 , 91 , which may be possible as more researchers heed calls to share unthresholded statistical maps 82 , 89 , 92 .…”
Section: Discussionmentioning
confidence: 99%