Are we approaching a post‐monolithic era?

Urban, Jiřı́

doi:10.1002/jssc.201901331

Cited by 12 publications

(13 citation statements)

References 45 publications

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“…However, a strong increase in peak width was observed with an increasing retention factor. This is likely to be related to a stationary mass transfer effect as earlier described by Huo et al., 47 later also referred to as a gel porosity effect 57–59 …”

Section: Methods Development and Key Applicationsmentioning

confidence: 75%

Recent developments and applications of polymer monolithic stationary phases

Eeltink

Meston

Švec

2021

Analytical Science Advances

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This review highlights the current trends and the most recent advances in the field of preparation and application of organic polymer‐based monolithic materials and covers literature published in 2020. A short historical background is provided and protocols to anchor monoliths covalently to the wall of the column/separation device are discussed. Furthermore, advances in tuning the macroporous structure and establishing its link to separation performance are conferred. Finally, method development and key applications using novel monolithic columns are discussed.

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Section: Methods Development and Key Applicationsmentioning

confidence: 75%

Recent developments and applications of polymer monolithic stationary phases

Eeltink

Meston

Švec

2021

Analytical Science Advances

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“…In 2013, Vlakh and Tennikova [6,7] updated progresses on monolithic IMERs and their corresponding applications. With the popularity of monolithic materials, the development of IMERs using diverse monoliths, including both organic and inorganic monoliths, has become more and more prominent in these years [8,9]. This review focuses on polymer (organic) monoliths, intending to give a comprehensive and critical discussion on its recent developments in the application for enzyme immobilization.…”

Section: Introductionmentioning

confidence: 99%

Flow‐through enzymatic reactors using polymer monoliths: From motivation to application

Mao

Fan

et al. 2021

Electrophoresis

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The application of monolithic materials as carriers for enzymes has rapidly expanded to the realization of flow‐through analysis and bioconversion processes. This expansion is partly attributed to the absence from diffusion limitation in many monoliths‐based enzyme reactors. Particularly, the relatively ease of introducing functional groups renders polymer monoliths attractive as enzyme carriers. After summarizing the motivation to develop enzymatic reactors using polymer monoliths, this review reports the most recent applications of such reactors. Besides, the present review focuses on the crucial characteristics of polymer monoliths affecting the immobilization of enzymes and the processing parameters dictating the performance of the resulting enzymatic reactors. This review is intended to provide a guideline for designing and applying flow‐through enzymatic reactors using polymer monoliths.

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“…The emergence of interest in polymer monoliths is due to their effectiveness as stationary phases in various types of separation and analytical processes that are overviewed Polymers 2021, 13, 1059 2 of 25 and discussed in some recent reviews [19][20][21][22]. At present, existing flow-through monoliths of various geometries (discs, rods, tubes, and capillary columns) with axial or radial flow have been developed for analytical and industrial applications [23][24][25][26].…”

Section: Introductionmentioning

confidence: 99%

“…Both these trends in the development and utilization of monolithic matrices are quite young, but have already been presented in the literature in a number of works. In contrast to flow-through monoliths, broadly reviewed in the literature from different point of views [4,[19][20][21][22]36,43,44], the summarization of achievements in the field of preparation and application of rigid macroporous monoliths in shape of thin layers have not been presented. Thus, the aim of this review is a first attempt to overview this topic.…”

Section: Introductionmentioning

confidence: 99%

Macroporous Polymer Monoliths in Thin Layer Format

2021

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Nowadays, macroporous polymer monoliths represent widely used stationary phases for a number of dynamic interphase mass exchange processes such as high-performance liquid chromatography, gas chromatography, electrochromatography, solid-phase extraction, and flow-through solid-state biocatalysis. This review represents the first summary in the field of current achievements on the preparation of macroporous polymer monolithic layers, as well as their application as solid phases for thin-layer chromatography and different kinds of microarray.

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Are we approaching a post‐monolithic era?

Abstract: Czech Republic, where he became an Associate Professor in 2018. In his research, he utilizes polymer monoliths to develop multifunctional miniaturized analytical systems.How to cite this article: Urban, J. Are we approaching a post-monolithic era?

Cited by 12 publications

References 45 publications

Recent developments and applications of polymer monolithic stationary phases

Recent developments and applications of polymer monolithic stationary phases

Flow‐through enzymatic reactors using polymer monoliths: From motivation to application

Macroporous Polymer Monoliths in Thin Layer Format

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