2022
DOI: 10.1007/s12274-022-4086-z
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Arginine-peptide complex-based assemblies to combat tumor hypoxia for enhanced photodynamic therapeutic effect

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Cited by 15 publications
(13 citation statements)
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“…Nitric oxide will be released, which will help to enhance cellular oxygen levels and prevent cells from respiring through their mitochondria. Thereby resolving the difficulty [106].…”
Section: Ph-responsive Targeted Pdt; Protoporphyrin IX (Ppix) Coupled...mentioning
confidence: 99%
“…Nitric oxide will be released, which will help to enhance cellular oxygen levels and prevent cells from respiring through their mitochondria. Thereby resolving the difficulty [106].…”
Section: Ph-responsive Targeted Pdt; Protoporphyrin IX (Ppix) Coupled...mentioning
confidence: 99%
“…Under light irradiation, PS produces oxygen free radicals or singlet oxygen, depending on its structure and the surrounding environment, and then promotes the release of NO from NO donors like L-arg. [129] Due to the lossless of PS during light irradiation, it can also be considered a catalytic reaction process. Ma et al reported an erythrocyte membrane-enveloped proteinic nanoparticles that biomimic NOS with coloading of photosensitizer IR783 and L-arg.…”
Section: Organic Nanomaterialsmentioning
confidence: 99%
“…PDT is based on photosensitizer to convert oxygen into cytotoxic-ROS under light irradiation (Hou et al., 2022 ). The mechanisms of photosensitizer generating ROS can be divided two types: (1) Photosensitizer transfers light energy to either tissue substrate and produce superoxide anion radicals (such as O 2 − and HO 2 ), which is called as Type I reaction; (2) Photosensitizer directly converts O 2 molecules into singlet oxygen ( 1 O 2 ), which is Type II reaction (Aniogo et al., 2019 ).…”
Section: Phototherapymentioning
confidence: 99%