Array-based chemical warfare agent discrimination via organophosphorus-H₂O₂ reaction-regulated chemiluminescence

Abstract

A chemical warfare agent sensor array based on organophosphorus-H2O2 reaction-regulated chemiluminescence is proposed.

Recent Progress in Sensor Arrays: From Construction Principles of Sensing Elements to Applications

“…119 Recently, an array-based CWA discrimination was realized based on organophosphorus-H 2 O 2 reaction-regulated chemiluminescence. 120 Disease Identification. Biomarkers are indicators that can determine the process of certain diseases, which are widely studied in clinical diagnosis and disease identification.…”

“…Subsequently, a colorimetric sensor array was proposed using iSense-proprietary 73-indicators as sensing units, achieving the identification of CWAs with an entirely automated workflow . Recently, an array-based CWA discrimination was realized based on organophosphorus-H 2 O 2 reaction-regulated chemiluminescence …”

Simple Chemical and Cholinesterase Methods for the Detection of Nerve Agents Using Optical Evaluation

“…The Schoenemann method of detecting organophosphorus CWAs is still of interest today, as evidenced by some new proposals to optimize the reaction, such as a colourimetric method with the extraction of the reaction product into chloroform for application in field laboratories [16], increasing the reaction temperature [32], or the use of a chemiluminescence sensor system MgAl-LDH)-luminol-H2O2 (LDH = layer double hydrolysis) [33]. The Schoenemann method is relatively simple and can be used well in both laboratory and field conditions.…”

Highly sensitive chemiluminescence sensors for the detection and differentiation of chemical warfare agents

“…18 The second work by Zhang et al presented a chemiluminescence sensor array able to differentiate between OPCWAs based on a reaction with their phosphorus atom, however, in a relative manner. 19 In recent years, in parallel to the development of various uorescence-based probes, Shabat's group has put major efforts to establish an array of chemiluminescence sensors based on Schaap's dioxetane, 20 which are able to identify various analytes. [21][22][23][24] This sensitive technique seemed to be a highly potential new tool for OPCWA detection.…”

“…18 The second work by Zhang et al presented a chemiluminescence sensor array able to differentiate between OPCWAs based on a reaction with their phosphorus atom, however, in a relative manner. 19…”