“…In the last years, a lot of studies analyzed pros and cons of these two types of cardioplegic solutions in the different areas of cardiac surgery (6), both in adults and in pediatrics (7,8), in order to find unique and shared indications but today the debate is still open especially in valve surgery. In fact, while literature swarms of clinical investigations about use of cardioplegic strategies in coronary artery bypass (CAB) surgery (9), there are few and conflicting studies comparing their use in valve surgery.…”