Arterial Switch Operation in the First Hours of Life Using Autologous Umbilical Cord Blood

Chasovskyi, Kyrylo; Fedevych, Oleg; Vorobiova, Ganna; Жовнір, В. А.; Maksimenko, A.S.; Boychenko, Olena; Lysak, Yuriy; Cohen, Gordon; Yemets, Illya

doi:10.1016/j.athoracsur.2012.01.104

Cited by 40 publications

(41 citation statements)

References 23 publications

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“…One study suggests that 3 days of age is the ideal time for an ASO [24]. Others suggest the ASO can be safely performed within hours of birth using autologous umbilical cord blood to prime the bypass circuit [36, 37]. These recommendations require longer follow-up and multi-institutional validation, but suggest that delays in performing the ASO should be minimized.…”

Section: Preoperative Carementioning

confidence: 99%

D-Transposition of the Great Arteries

Villafañe

Lantin‐Hermoso

Bhatt

et al. 2014

Journal of the American College of Cardiology

246

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Objectives This paper aims to update clinicians on “Hot Topics” in the management of patients with d-transposition of the great arteries (D-TGA) in the current surgical era. Background The arterial switch operation (ASO) has replaced atrial switch procedures for D-TGA and 90% of patients now reach adulthood. Methods The Adult Congenital and Pediatric Cardiology Council (ACPC) of the American College of Cardiology assembled a team of experts to summarize current knowledge on genetics, prenatal diagnosis, surgical timing, balloon atrial septostomy (BAS), prostaglandin therapy (PGE), intraoperative techniques, imaging, coronary obstruction, arrhythmias, sudden death, aortic dilation and regurgitation (AR), neurodevelopmental (ND) issues and lifelong care of D-TGA patients. Results In simple D-TGA, 1) familial recurrence risk is low; 2) children diagnosed prenatally have improved cognitive skills compared with those diagnosed postnatally; 3) echocardiography helps to identify risk factors; 4) routine use of BAS and PGE may not be beneficial in some cases; 5) early ASO improves outcomes and reduces costs with a low mortality. Single or intramural coronary arteries remain risk factors; 6) post-ASO arrhythmias and cardiac dysfunction should raise suspicion of coronary insufficiency; 7) coronary insufficiency and arrhythmias are rare but associated with sudden death; 8) early and late-onset ND abnormalities are common; 9) AR and aortic root dilation are well tolerated; and 10) the aging ASO patient may benefit from “exercise-prescription” rather than restriction. Conclusions Significant strides have been made in understanding risk factors for cardiac, ND and other important clinical outcomes after ASO.

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Section: Preoperative Carementioning

confidence: 99%

D-Transposition of the Great Arteries

Villafañe

Lantin‐Hermoso

Bhatt

et al. 2014

Journal of the American College of Cardiology

246

View full text Add to dashboard Cite

show abstract

“…12 Chasovskyi et al demonstrated the feasibility of using umbilical cord blood in 21 patients undergoing ASO at a mean age of 11 hours. 13 Compared to 40 control patients with a mean age at ASO of 7.7 days, the early repair group had a lower total LOS. Several other studies have documented excellent outcomes and provide recommendations regarding management of patients with d-TGA/IVS.…”

Section: Discussionmentioning

confidence: 96%

Transposition of the Great Arteries—Outcomes and Time Interval of Early Neonatal Repair

Cain

Cao

Ghanayem

et al. 2014

World J Pediatr Congenit Heart Surg

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“…We read with great interest the recent article by Chasovskyi and colleagues [1] about autologous umbilical cord blood (UCB) used in neonatal cardiac operations. In the last year, a member of the author's team published an article about their innovative technique [2].…”

Section: An Innovative Technique To the Neonatal Arterial Switch Opermentioning

confidence: 97%

“…We thank Dr Liu and colleagues [1] for their interest in our article [2]. In our institution, the arterial switch operation (ASO) in the first hours of life by the use of autologous umbilical cord blood transfusion (AUCBT) is routinely implemented for prenatally diagnosed transposition of the great arteries.…”

Section: Reply To the Editormentioning

confidence: 98%