Artificial intelligence assisted label-free surface-enhanced Raman scattering detection of early-stage cancer-derived exosomes based on g-C3N4/Ag hybrid substrate prepared by electro-synthesis

Zhao, Jialong; Chen, Junfeng; Tang, Jing; Dai, Yasheng; Wang, Shiyuan; Fan, Weiqi; Pang, Bairen; Jiang, Junhui; Gu, Chenjie; Jiang, Tao; Wu, Kerong

doi:10.1016/j.cej.2024.155526

Chemical Engineering Journal

2024

DOI: 10.1016/j.cej.2024.155526

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Artificial intelligence assisted label-free surface-enhanced Raman scattering detection of early-stage cancer-derived exosomes based on g-C3N4/Ag hybrid substrate prepared by electro-synthesis

Jialong Zhao,

Junfeng Chen,

Jing Tang

et al.

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Innovative Applications and Perspectives of Surface‐Enhanced Raman Spectroscopy Technology in Biomedicine

Xu,

Xie,

Liu

et al. 2024

Small

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Surface‐enhanced Raman spectroscopy (SERS) has become a revolutionary technique in the biomedical field, providing unparalleled sensitivity for the detection and characterization of biological samples. In this review, recent SERS innovations are comprehensively discussed, including advanced substrate materials, different SERS detection strategies, and multimodal approaches that combine SERS with other biotechnologies. Among them, the role of SERS in the accurate diagnosis of tumors is highlighted, which has promoted accurate molecular analysis and real‐time monitoring of treatment effects. In addition, the growing potential of SERS in the treatment of chronic diseases such as cardiovascular disease, diabetes, and neurodegenerative diseases is discussed. Moreover, the integration with microfluidic chip systems for precise single‐cell analysis is presented. To give a forward‐looking view, the key challenges faced by SERS technology are also proposed, and possible solutions to overcome these obstacles are provided.

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Innovative Applications and Perspectives of Surface‐Enhanced Raman Spectroscopy Technology in Biomedicine

Xu,

Xie,

Liu

et al. 2024

Small

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Hydrogel based flexible wearable sweat sensor for SERS-AI monitoring treatment effect of lung cancer

Chen,

Liu,

et al. 2025

Sensors and Actuators B: Chemical

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Artificial intelligence assisted label-free surface-enhanced Raman scattering detection of early-stage cancer-derived exosomes based on g-C3N4/Ag hybrid substrate prepared by electro-synthesis

Cited by 2 publications

References 60 publications

Innovative Applications and Perspectives of Surface‐Enhanced Raman Spectroscopy Technology in Biomedicine

Innovative Applications and Perspectives of Surface‐Enhanced Raman Spectroscopy Technology in Biomedicine

Hydrogel based flexible wearable sweat sensor for SERS-AI monitoring treatment effect of lung cancer

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