Assembling photosensitive capsules by phthalocyanines and polyelectrolytes for photodynamic therapy

Yu, Zhong‐Zhen; Wang, Xiao Li; Yang, Yunjie; Chen, Jianfeng; Fu, Ji-Wen; Tao, Xia

doi:10.1016/j.polymer.2011.02.020

Cited by 19 publications

(6 citation statements)

References 41 publications

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“…Metachromic cationic dye methylene blue was investigated for organization in the LbL framework [26]. In addition, photocleavable chromophores [27], laser absorbing dye (IR-806) [28], bacteriorhodopsin [29], phthalocyanine [30], porphyrin [31,32], and naphthalocyanine [33] have been also incorporated in microcapsules for remote opening by laser light, but it was also noticed that inorganic nanoparticles appeared to be much more effective laser light absorbers…”

Section: Incorporation Of Dyes In Layer-by-layer (Lbl) Coatings-bringing Multifunctionality Through Organic Moietiesmentioning

confidence: 99%

Nanoparticles in Polyelectrolyte Multilayer Layer-by-Layer (LbL) Films and Capsules—Key Enabling Components of Hybrid Coatings

Lengert

Kol'tsov²,

et al. 2020

Coatings

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Originally regarded as auxiliary additives, nanoparticles have become important constituents of polyelectrolyte multilayers. They represent the key components to enhance mechanical properties, enable activation by laser light or ultrasound, construct anisotropic and multicompartment structures, and facilitate the development of novel sensors and movable particles. Here, we discuss an increasingly important role of inorganic nanoparticles in the layer-by-layer assembly—effectively leading to the construction of the so-called hybrid coatings. The principles of assembly are discussed together with the properties of nanoparticles and layer-by-layer polymeric assembly essential in building hybrid coatings. Applications and emerging trends in development of such novel materials are also identified.

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Section: Incorporation Of Dyes In Layer-by-layer (Lbl) Coatings-bringing Multifunctionality Through Organic Moietiesmentioning

confidence: 99%

Nanoparticles in Polyelectrolyte Multilayer Layer-by-Layer (LbL) Films and Capsules—Key Enabling Components of Hybrid Coatings

Lengert

Kol'tsov²,

et al. 2020

Coatings

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“…Recently, functionalization of capsules with porphyrins and subsequent opening of capsules by a laser was demonstrated, 30 and experiments with cell cultures were performed. 31 In addition, in-depth studies of photostability of phthalocyanine molecules were also conducted. 32 (7) Near-infrared absorbing dyes basically use the same principles as noble metal nanoparticles.…”

Section: Multifunctionality: Functionalization Of the Polymeric Shell...mentioning

confidence: 99%

Encapsulation, release and applications of LbL polyelectrolyte multilayer capsules

2011

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Ever since their invention in 1998, polyelectrolyte multilayer micro- and nano-capsules have impacted various areas of biology, chemistry and physics. Here we highlight progress achieved since the millennium in the areas of encapsulation in and release from microcapsules, describe various structures including multicompartment and anisotropic constructs, and provide examples of several applications in biology. We also describe application areas such as drug delivery, intracellular trafficking, enzyme-catalyzed reactions, mechano-biology which benefited from recent developments in the area of polyelectrolyte multilayer capsules.

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“…A very interesting class of material for delivery and release of active substances is polyelectrolyte microcapsules . The versatility of layer‐by‐layer assembly (LbL) permits incorporation of various materials into polymeric shell from organic molecules to inorganic nanoparticles , which provide multifunctionality of polyelectrolyte multilayer capsules. As a result, the permeability of multifunctional capsules can be controlled by applying various external stimuli, such as laser light and magnetic field , ultrasound , enzymatic reactions , mechanical deformation , thereby release of a cargo on demand.…”

Section: Introductionmentioning

confidence: 99%

Multifunctional polyelectrolyte microcapsules as a contrast agent for photoacoustic imaging in blood

Yashchenok

Jose

Trochet

et al. 2016

Journal of Biophotonics

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The polyelectrolyte microcapsules that can be accurate either visualized in biological media or in tissue would enhance their further in vivo application both as a carrier of active payloads and as a specific sensor. The immobilization of active species, for instance fluorescent dyes, quantum dots, metal nanoparticles, in polymeric shell enables visualization of capsules by optical imaging techniques in aqueous solution. However, for visualization of capsules in complex media an instrument with high contrast modality requires. Herein, we show for the first time photoacoustic imaging (PAI) of multifunctional microcapsules in water and in blood. The microcapsules exhibit greater photoacoustic intensity compare to microparticles with the same composition of polymeric shell presumably their higher thermal expansion. Photoacoustic intensity form microcapsules dispersed in blood displays an enhancement (2-fold) of signal compare to blood. Photoacoustic imaging of microcapsules might contribute to non-invasive carrier visualization and further their in vivo distribution.

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Assembling photosensitive capsules by phthalocyanines and polyelectrolytes for photodynamic therapy

Cited by 19 publications

References 41 publications

Nanoparticles in Polyelectrolyte Multilayer Layer-by-Layer (LbL) Films and Capsules—Key Enabling Components of Hybrid Coatings

Nanoparticles in Polyelectrolyte Multilayer Layer-by-Layer (LbL) Films and Capsules—Key Enabling Components of Hybrid Coatings

Encapsulation, release and applications of LbL polyelectrolyte multilayer capsules

Multifunctional polyelectrolyte microcapsules as a contrast agent for photoacoustic imaging in blood

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