Assembly and Functionalization of DNA−Polymer Microcapsules

Cavalieri, Francesca; Postma, Almar; Lee, Lillian; Caruso, Frank

doi:10.1021/nn800705m

Cited by 106 publications

(83 citation statements)

References 32 publications

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“…Styrene derivatives subjected to RAFT polymerization 348 [100,199] O 349 [138] O N N N 350 [158,309] N VBTAC 351 [159] Cl Ϫ Nϩ 352 [459] HN O 353 [321] O F F F F 354 [313] O F F F F 355 [313] [244] VBTPC 359 [34] Cl Ϫ P ϩ 360 [244] 361 [250] O N O 362 [207] O O O 363 [134] O O O Fe 364 [102] N 365 [102] N Table 23. Vinyl derivatives subjected to RAFT polymerization 366 [380] N 367 [380] N 368 [380] N 369 [390] N O O G. Moad, E. Rizzardo, and S. H. Thang [111,135] 370 [135,146] 375 [136] 376 [195] 377 [150] 378 [410] O O (H 3 C) 3 Si 372 [338,346,347] 373 [201] 374 [459] O [466] NAS 380 [160,299,317,345,347] 381 [178] 382 [222] [149,…”

Section: End-functional Polymers and End-group Transformationsmentioning

confidence: 99%

“…RAFT polymerization has been used to synthesize the scaffolds for attachment of biopolymers by copolymerization of monomers shown in Table 24 (azide or alkyne functionality), Table 25 (active ester functionality, e.g., Scheme 29) for attachment of therapeutic agents, [317] peptides, [160,317] or DNA, [347] or Table 26 (e.g., pyridyl disulfide functionality (391), Scheme 30) for attachment of thiol residues of proteins (e.g., BSA), [162] or drug molecules. [161] The production of such scaffolds by RAFT and other RDRP processes for post polymerization modification has recently been reviewed.…”

Section: Grafting-to Processesmentioning

confidence: 99%

See 1 more Smart Citation

Living Radical Polymerization by the RAFT Process - A Second Update

Moad¹,

Rizzardo²,

Thang³

2009

Aust. J. Chem.

906

720

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This paper provides a second update to the review of reversible deactivation radical polymerization achieved with thiocarbonylthio compounds (ZC(=S)SR) by a mechanism of reversible addition-fragmentation chain transfer (RAFT) that was published in June 2005 (Aust. J. Chem. 2005, 58, 379-410). The first update was published in November 2006 (Aust. J. Chem. 2006, 59, 669-692). This review cites over 500 papers that appeared during the period mid-2006 to mid-2009 covering various aspects of RAFT polymerization ranging from reagent synthesis and properties, kinetics and mechanism of polymerization, novel polymer syntheses and a diverse range of applications. Significant developments have occurred, particularly in the areas of novel RAFT agents, techniques for end-group removal and transformation, the production of micro/nanoparticles and modified surfaces, and biopolymer conjugates both for therapeutic and diagnostic applications.

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Section: End-functional Polymers and End-group Transformationsmentioning

confidence: 99%

Section: Grafting-to Processesmentioning

confidence: 99%

Living Radical Polymerization by the RAFT Process - A Second Update

Moad¹,

Rizzardo²,

Thang³

2009

Aust. J. Chem.

906

720

View full text Add to dashboard Cite

show abstract

“…[19][20][21] It can well interact with graphitic carbon materials such as carbon nanotubes through π -stacking to provide functional groups while retaining intact structure of the carbon materials. [ 22 , 23 ] Very recently it has been demonstrated by us to tailor nanostructured FePO 4 on carbon nanotubes for high performance lithium-ion batteries.…”

mentioning

confidence: 99%

DNA‐Functionalized Graphene to Guide Growth of Highly Active Pd Nanocrystals as Efficient Electrocatalyst for Direct Formic Acid Fuel Cells

Guo

Zhang

Miao

et al. 2012

Advanced Energy Materials

196

109

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“…Besides nanosized systems, the double-helix formation of DBCs was exploited for the preparation of microcapsules. 42 By alternating assembly of T 30 -b-PNIPAM and A 30 -b-PNIPAM layers around a silicon particle, subsequent PEG functionalization and removal of the silica core particle, stable microcapsules were obtained. These hollow nanocontainers are envisioned to find applications in controlled delivery and release of therapeutics.…”

Section: Dbc Micelles As Templates For Chemical Reactions and Virus Cmentioning

confidence: 99%

DNA Block Copolymers: Functional Materials for Nanoscience and Biomedicine

2012

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W e live in a world full of synthetic materials, and the development of new technologies builds on the design and synthesis of new chemical structures, such as polymers. Synthetic macromolecules have changed the world and currently play a major role in all aspects of daily life. Due to their tailorable properties, these materials have fueled the invention of new techniques and goods, from the yogurt cup to the car seat belts. To fulfill the requirements of modern life, polymers and their composites have become increasingly complex. One strategy for altering polymer properties is to combine different polymer segments within one polymer, known as block copolymers. The microphase separation of the individual polymer components and the resulting formation of well defined nanosized domains provide a broad range of new materials with various properties. Block copolymers facilitated the development of innovative concepts in the fields of drug delivery, nanomedicine, organic electronics, and nanoscience.Block copolymers consist exclusively of organic polymers, but researchers are increasingly interested in materials that combine synthetic materials and biomacromolecules. Although many researchers have explored the combination of proteins with organic polymers, far fewer investigations have explored nucleic acid/polymer hybrids, known as DNA block copolymers (DBCs). DNA as a polymer block provides several advantages over other biopolymers. The availability of automated synthesis offers DNA segments with nucleotide precision, which facilitates the fabrication of hybrid materials with monodisperse biopolymer blocks. The directed functionalization of modified single-stranded DNA by WatsonÀCrick base-pairing is another key feature of DNA block copolymers. Furthermore, the appropriate selection of DNA sequence and organic polymer gives control over the material properties and their self-assembly into supramolecular structures. The introduction of a hydrophobic polymer into DBCs in aqueous solution leads to amphiphilic micellar structures with a hydrophobic polymer core and a DNA corona.In this Account, we discuss selected examples of recent developments in the synthesis, structure manipulation and applications of DBCs. We present achievements in synthesis of DBCs and their amplification based on molecular biology techniques. We also focus on concepts involving supramolecular assemblies and the change of morphological properties by mild stimuli. Finally, we discuss future applications of DBCs. DBC micelles have served as drug-delivery vehicles, as scaffolds for chemical reactions, and as templates for the self-assembly of virus capsids. In nanoelectronics, DNA polymer hybrids can facilitate size selection and directed deposition of single-walled carbon nanotubes in field effect transistor (FET) devices.

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Assembly and Functionalization of DNA−Polymer Microcapsules

Cited by 106 publications

References 32 publications

Living Radical Polymerization by the RAFT Process - A Second Update

Living Radical Polymerization by the RAFT Process - A Second Update

DNA‐Functionalized Graphene to Guide Growth of Highly Active Pd Nanocrystals as Efficient Electrocatalyst for Direct Formic Acid Fuel Cells

DNA Block Copolymers: Functional Materials for Nanoscience and Biomedicine

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