Assessing satisfaction in men with premature ejaculation after dapoxetine treatment in real-world practice

Jiann, Bang‐Ping; Huang, Yuanyuan

doi:10.1111/ijcp.12700

Cited by 16 publications

(17 citation statements)

References 41 publications

(94 reference statements)

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“…In this study, dapoxetine was found to be the most widely prescribed medication. Jiann and Huang [21] reported that the satisfaction rate and response rate to dapoxetine treatment were 45.0% and 74.6%, respectively, demonstrating a gap between the efficacy of dapoxetine and patient expectations regarding the treatment of PE. However, in this study, off-label medications were found to be widely used, especially in non-hospital clinics, which may be due to the relatively expensive price of dapoxetine and pressure from patients who want to keep taking previous medications.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and Treatment of Premature Ejaculation by Urologists in South Korea

Seo

Jeh

Choi

et al. 2016

World J Mens Health

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PurposeThis study discusses the treatment of premature ejaculation (PE) using various approaches with the goal of evaluating the methods of diagnosis and treatment of PE in clinical practice in 2014 in South Korea.Materials and MethodsWe surveyed 200 urologists and andrologists who treated patients with PE from July 1, 2014 to July 29, 2014 using an online questionnaire. The questionnaire was composed of 4 parts: disease, comorbidities, diagnosis, and treatment. Using the answers to this survey, current trends in the diagnosis and treatment of PE were investigated using weighted averages.ResultsThe median number per month of patients who were diagnosed with PE was 14 patients (interquartile range, 7~24). The time to ejaculation necessary for a diagnosis of PE was considered to be <1 minute by 12% of respondents, <2 minutes by 27%, <3 minutes by 28%, <5 minutes by 13%, and 20% stated that diagnosis was based on a patient's subjective complaint. The treatment methods preferred by PE patients were reported to be pharmacological treatment (87%), surgical treatment (9.5%), and behavioral management (3.5%). The treatment methods used by respondents were pharmacological treatment (77%), surgical treatment (15%), and behavioral management (14%). The most commonly used pharmacological treatment was the oral administration of dapoxetine (97%).ConclusionsIn 2014 in South Korea, various methods were used to diagnose and treat PE. The most commonly used treatment for PE was the oral administration of dapoxetine. It was also found that surgical treatment was applied in some cases.

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Section: Discussionmentioning

confidence: 99%

Diagnosis and Treatment of Premature Ejaculation by Urologists in South Korea

Seo

Jeh

Choi

et al. 2016

World J Mens Health

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“…Because PE has a multifactorial etiology (1) and a substantial proportion of PE patients also have comorbidity (69,73), the management of patients with PE may be complex and may require a multidisciplinary approach. Optimal treatment outcomes can be achieved through a holistic approach by using appropriate etiology-specific treatments combined with dapoxetine treatments (2).…”

Section: Optimizing Dapoxetine Treatment For Premature Ejaculation (Pe)mentioning

confidence: 99%

“…Optimal treatment outcomes can be achieved through a holistic approach by using appropriate etiology-specific treatments combined with dapoxetine treatments (2). A phosphodiesterase type 5 (PDE5) inhibitor can be used with dapoxetine in the treatment of ED and coexisting PE (73,74). When psychogenic or relationship factors are present, psychological behavioral therapy can be combined with dapoxetine treatment in an integrated treatment program to manage both the emotional and physical aspects of PE (60,62).…”

Section: Optimizing Dapoxetine Treatment For Premature Ejaculation (Pe)mentioning

confidence: 99%

“…The number of sexual attempts and dapoxetine dosages are critical factors associated with the extent of ejaculation delaying (68,71,73). The aforementioned integrated analysis of data from five phase III trials of dapoxetine revealed that the effects of dapoxetine could be observed after the first dose, with the most favorable outcome being obtained after 12 weeks of treatment (68).…”

Section: Management Of Initial Non-response To Dapoxetine Treatment Imentioning

confidence: 99%

“…In the PAUSE study, 17.7% of patients with PE in the dapoxetine treatment group required a higher dose of 60 mg at visits 2–4 (70). Jiann and Huang demonstrated that 42.9% of patients with unsatisfactory response to dapoxetine (30 mg) could benefit from a 60-mg dose (73). However, no clinical study has demonstrated whether dapoxetine (90 or 120 mg) can salvage dapoxetine (60 mg) non-responders.…”

Section: Management Of Initial Non-response To Dapoxetine Treatment Imentioning

confidence: 99%

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The office management of ejaculatory disorders

Jiann

2016

Transl. Androl. Urol.

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Premature ejaculation (PE), delayed ejaculation (DE), anejaculation (AE) and retrograde ejaculation (RE) are four main ejaculatory disorders (EjDs) observed in clinical practice. Despite their high prevalence, EjDs remain underdiagnosed and undertreated. Primary care physicians should incorporate the discussion of sexual health topics into routine visits to facilitate EjD diagnosis and treatment. Because the causes of EjDs are multifactorial, the management of EjDs is etiology-specific and may require a holistic approach. Dapoxetine, a selective serotonin reuptake inhibitor, is the only drug approved for on-demand treatment of lifelong and acquired PE. In clinical practice, scheduled follow-up visits, risk factor treatment, appropriate dose escalation, adequate sexual attempts, patient education, and partner involvement are critical factors responsible for optimal overall management of PE and dapoxetine treatment outcomes.

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