Assessing the diagnostic accuracy (DA) of the Spanish version of the informant-based AD8 questionnaire

Pardo, Cristóbal Carnero; Cotarelo, R. de la Vega; Alcalde, S. López; Aparicio, C. Martos; Carrillo, R. Vílchez; Gavilán, Eduardo; Galvin, James E.

doi:10.1016/j.nrleng.2012.03.013

Cited by 26 publications

(14 citation statements)

References 25 publications

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“…40 Researchers have observed higher levels of sensitivity when validating the AD8 with Latin American samples. Carnero-Pardo and colleagues’ 41 large Spanish study (n = 401) yielded 93% sensitivity and 81% specificity cognitive impairment with a cutoff score of 3/4, while Blanco et al, 95 working with a notably smaller Argentinian sample (n = 62), found that a cutoff score of 2 best balanced sensitivity and specificity at 80% and 83% when detecting dementia, and noted minor differences in translation choices from the Spanish study. Specificity detecting MCI was considerably lower at 44%.…”

Section: Informant Report Measuresmentioning

confidence: 96%

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

Burke

Grudzien

Burgess

et al. 2020

J Geriatr Psychiatry Neurol

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Increasing rates of dementia spectrum disorders among Spanish-speaking geriatric populations necessitate the development of culturally appropriate cognitive screening tests that can identify neurodegenerative disorders in their earliest stages when emerging disease-modifying treatments are most likely to be effective. This scoping review identified 26 brief Spanish language cognitive screening tools (<20 minutes) by searching academic databases using a combination of search terms. Results suggest that the Mini-Mental Status Examination and Montreal Cognitive Assessment appear to be less valid than other screeners. Instruments such as the 7-Minute Screen and Mini-Cog evidence higher classification rates of dementia, while Phototest detected mild cognitive impairment at higher rates more consistently than other screeners. Different sensitivity and specificity outcomes and cutoffs were observed when the same cognitive screener was evaluated in different countries. Results indicate that it is imperative to increase nation-specific validation and normative data for these instruments to best serve diverse populations.

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Section: Informant Report Measuresmentioning

confidence: 96%

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

Burke

Grudzien

Burgess

et al. 2020

J Geriatr Psychiatry Neurol

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“…The AD8 has been widely adopted, for example to assess for cognitive impairment in a geriatric emergency department, 7 and has been translated into a number of languages. 8 –11 AD8 may be more effective than the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), another informant-based questionnaire, for detecting cognitive impairment. 12…”

Section: Introductionmentioning

confidence: 99%

AD8 Informant Questionnaire for Cognitive Impairment

Larner

2015

J Geriatr Psychiatry Neurol

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The diagnostic accuracy of the AD8 informant questionnaire for cognitive impairment was assessed in patients referred to a dedicated memory clinic. This pragmatic prospective study of consecutive referrals attending with an informant who completed AD8 (n = 212) lasted 12 months. Diagnosis used standard clinical diagnostic criteria for dementia and mild cognitive impairment as reference standard (prevalence of cognitive impairment = 0.62). The AD8 proved acceptable to informants, was quick, and easy to use. Using the cutoff of ≥2/8, AD8 was highly sensitive (0.97) for diagnosis of cognitive impairment but specificity was poor (0.17). Combining AD8 with either the Mini-Mental State Examination or the Six-Item Cognitive Impairment Test showed little additional diagnostic benefit. In conclusion, AD8 is very sensitive for cognitive impairment in a memory clinic but specificity may be inadequate.

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“…The primary objective of the AIPAD-online study was the evaluation of the feasibility of the electronic version of two questionnaires for dementia screening, namely, IQCODE (Informant Questionnaire on Cognitive Decline in the Elderly) short version ( Jorm, 1994 ), and AD8 (Alzheimer’s Disease) ( Galvin et al, 2007 ) and their correlation with the traditional paper version previously translated and validated into Spanish ( Morales Gonzalez et al, 1992 ; Morales et al, 1995 ; Del-Ser et al, 1997 ; Carnero Pardo et al, 2013 ). Both questionnaires were completed by the same informant.…”

Section: Methodsmentioning

confidence: 99%

Does Your Loved One With Cognitive Symptoms Need to See a Doctor? Check It Online

Agüera-Ortíz

Martı́n-Carrasco

Arriola-Manchola

et al. 2022

Front. Comput. Neurosci.

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Widespread access to emerging information and communication technologies (ICT) allows its use for the screening of diseases in the general population. At the initiative of the Spanish Confederation of Associations of Families of People with Alzheimer’s disease and other dementias (CEAFA), a website (http://www.problemasmemoria.com) has been created that provides information about Alzheimer’s disease and includes questionnaires to be completed by family or friends concerned about memory problems of a relative. A cross-sectional, randomized, multicenter study was performed to evaluate feasibility, validity, and user satisfaction with an electronic method of completion vs. the current method of paper-based questionnaires for clinically dementia screening completed by the informants: the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) and the Alzheimer’s disease-8 screening test (AD8). A total of 111 pairs were recruited by seven memory clinics. Informants completed IQCODE and AD8 questionnaires both in their paper and electronic versions. The correlation between paper and electronic versions was significantly positive for IQCODE (r = 0.98; p < 0.001) and AD8 (r = 0.96; p < 0.001). The execution time did not differ significantly, and participants considered their use equally easy. This study shows that an electronic version of the IQCODE and AD8 questionnaires is suitable for its online use via the internet and achieves the same results as the traditional paper versions.

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Assessing the diagnostic accuracy (DA) of the Spanish version of the informant-based AD8 questionnaire

Cited by 26 publications

References 25 publications

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

AD8 Informant Questionnaire for Cognitive Impairment

Does Your Loved One With Cognitive Symptoms Need to See a Doctor? Check It Online

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