Assessing the Functional Status of Older Cancer Patients in an Ambulatory Care Visit

Overcash, Janine

doi:10.3390/healthcare3030846

Cited by 15 publications

(9 citation statements)

References 93 publications

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“…It is argued that functional status could be the cause of reflecting affective symptoms in PBT (Hill et al, 2016). This was supported by Overcash's (2015) study, which found that cancer patients diagnosed with depression were more likely to report problems with cognitive deficits and activities of daily living (ADL). In a similar vein, Huang et al (2017) conducted a meta-analysis study to investigate the association between affective symptoms and brain tumor using a screening test battery, including BDI-II and HADS.…”

Section: Brain Tumor In Saudi Arabiamentioning

confidence: 92%

Depression and Anxiety Disorders in a Sample of Saudi Persons with Brain Tumor

Alanazi¹,

Saleh²,

Awadalla³

et al. 2020

GJHS

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BACKGROUND: Depression and anxiety (DA) are common in persons with brain tumor (PBT) and are associated with neurocognitive deficits. The terms DA and affective disorders are often used interchangeably in this study. Objective: This was a pilot study, conducted with the purpose of better assessing DA symptoms in association with socioeconomic and clinical characteristics in PBT. METHOD: A cross-sectional study was conducted on a sample of PBT (N = 102), recruited from a neurosurgical department. The tools employed were the Beck Depression Inventory-II (BDI-II) and the Hospital Anxiety and Depression Scale (HADS). The self-rating instruments proved feasible and reliable in screening for the severity of DA symptoms. The HADS is designed to measure the severity of anxiety and depressive symptoms in non-psychiatric hospital outpatients and does not assess the common somatic symptoms of these two disorders. The BDI-II evaluates the severity of depressive symptoms with items related to physical symptoms. RESULTS: Although our study did not, for the most part, yield results of statistical significance, it, however, demonstrated that anxiety and depressive disorders existed in PBT, showing a relatively higher rate in age groups 30–49 years. CONCLUSION: It was unclear whether these symptoms were invalidated by response bias, participant’s functional status, natural reaction to a fearing situation or just presentation of pseudodepression arose as a result of organic deficits. There is a need for further research to examine these factors.

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Section: Brain Tumor In Saudi Arabiamentioning

confidence: 92%

Depression and Anxiety Disorders in a Sample of Saudi Persons with Brain Tumor

Alanazi¹,

Saleh²,

Awadalla³

et al. 2020

GJHS

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“…17 The FACT-G assesses QoL along a Likert scale in four domains of well-being: physical, social/ family, emotional, and functional. The scale has been validated for use in multiple populations, including older cancer patients [18][19][20] and early stage BCS. 21 The FACT-B, a version specific for BCS, 22 adds questions to FACT-G which address QoL issues that are common sequelae of breast cancer.…”

Section: Introductionmentioning

confidence: 99%

Quality of life outcomes from a randomized controlled trial of patient navigation in Latina breast cancer survivors

et al. 2020

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Introduction Breast cancer survivorship is a life‐long process involving challenges to health‐care communities and individuals, especially Latinas. Patient Navigation has shown some success in meeting these challenges. The purpose of this study was to compare the effects of an enhanced Patient Navigation program (Intervention; PN+) vs Control (PN) over time on general cancer and breast cancer‐specific quality of life (QoL) in Latina breast cancer survivors (BCS). Methods We conducted a 2‐year, two‐arm randomized controlled trial of the “Staying Healthy” program among Latina BCS. The design compared PN+ vs PN over time. We recruited 60 patients into each study arm and randomized them by sequential numerical assignment. PN+ participants received culturally tailored educational materials and active, personalized Patient Navigation services, including phone calls, transportation, and care coordination. PN participants were navigated only upon request. Primary outcomes included general cancer (Functional Assessments of Cancer Therapy [FACTS]‐G) and breast cancer‐specific (FACT‐B) QoL. Results PN+ participants had significantly improved QoL measures compared to PN at 6‐month follow‐up on all subscales (P‐values .007‐.04) except physical well‐being (PWB; P = .11). Intervention effect size coefficient (standard error) for FACT‐G overall was 7.9 (3.1); P = .01. For FACT‐B, it was 10.9 (3.9); P = .006. Again, all subscales showed significant effects [range 1.7‐3.1 (0.8‐1.2); P‐values .006‐.04], except for PWB [1.5 (1.0); P = .16] and social/family well‐being (SWB) [2.1 (1.1); P = .06]. There were no differences between groups at baseline. Discussion Multiple cultural, psychosocial, and socioeconomic variables contributing to these intervention effects will be addressed in future studies. As the national BCS population continues to increase, more Patient Navigation‐focused partnerships among patients, health‐care professionals, research groups, and community organizations are needed to improve BCS experiences. The Staying Healthy program has the potential to serve as a national survivorship care model for improving Latina BCS QoL.

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“…The number of older patients with cancer is increasing due to the aging of the population. Aging is associated with a progressive decline in the functional reserve of many organ systems and increased incidence of multimorbidity, including cancer [1][2][3]. The prevalence of comorbidity in older patients with cancer varies from 36 to 94% [4][5][6][7] Comorbidity impacts survival, stage at diagnosis and risk of chemotherapy-related toxicity [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

“…30s CST: 30 s Chair Stand Test, CCI: Charlson Comorbidity Index, OMC: Orientation-Memory-Concentration, MNA: Mini Nutritional Assessment.a Strength b21 kg for men and b 15 kg for women considered abnormal[3].…”

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confidence: 99%

The impact of comprehensive geriatric assessment for optimal treatment of older patients with cancer: A randomized parallel-group clinical trial

Nadaraja

Matzen

Jørgensen

et al. 2020

Journal of Geriatric Oncology

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The aim was to investigate if oncologic treatment decision based on G8 screening followed by comprehensive geriatric assessment (CGA) and a multidisciplinary team conference in patients with G8 ≤ 14 was better than treatment decision based on standard assessment. ClinicalTrials.gov Identifier: NCT02671994. Materials and Methods: From January 2016 to June 2018, 96 patients with cancer, aged ≥70 years, were included. Patients were randomized to treatment decision based on the oncologist's clinical judgement (control) or based on screening with G8. If G8 N 14 treatment decision was made as in the control group and if G8 ≤ 14, patients were referred to CGA including intervention as needed and treatment decision after a multidisciplinary team conference (MDT). Results: The study was closed early. 47 patients were randomized to the control group and 49 to the intervention group; 28 had a G8 ≤ 14, 24 of whom attended CGA. In the intervention group 48% completed treatment as planned compared to 54% in the control group (p = .208). Thirty-eight percent experienced grade 3-4 toxicity in the control group compared with only 20% in the intervention group (p = .055). Median overall survival (OS) was 14.2 months in the control group and 19.1 months in the intervention group (p = .911). Median progression-free survival (PFS) was 9.0 months in the control group and 7.8 months for the intervention group (p = .838). Conclusion: Treatment decision based on G8 screening followed by CGA had no impact on completion rate of planned oncologic treatment, OS or PFS, but resulted in a borderline significant lower incidence of grade 3-4 toxicity.

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Assessing the Functional Status of Older Cancer Patients in an Ambulatory Care Visit

Cited by 15 publications

References 93 publications

Depression and Anxiety Disorders in a Sample of Saudi Persons with Brain Tumor

Depression and Anxiety Disorders in a Sample of Saudi Persons with Brain Tumor

Quality of life outcomes from a randomized controlled trial of patient navigation in Latina breast cancer survivors

The impact of comprehensive geriatric assessment for optimal treatment of older patients with cancer: A randomized parallel-group clinical trial

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