Assessment of human exposure and human health effects after indoor application of methyl parathion in Lorain County, Ohio, 1995-1996.

Rubin, Carol; Esteban, Emilio; Kieszak, Stephanie; Hill, Robert H.; Dunlop, Boadie W.; Yacovac, Rebecca; Trottier, Janine; Boylan, Kathy; Tomasewski, Terri; Pearce, Ken

doi:10.1289/ehp.02110s61047

Cited by 37 publications

(15 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Medical students are often taught to associate OP poisoning with the acronym SLUDGE-salivation, lacrimation, urination, defecation, gastrointestinal distress, and emesis. Unfortunately these are all fairly generic symptoms that would not prompt an emergency caregiver to consider OP poisoning unless the medical history suggested OP exposure [10,11].…”

Section: Introductionmentioning

confidence: 99%

Correlation between Serum Creatine Phosphokinase and Severity of Acute Organophosphorus Poisoning: A Prospective Clinical Study (2012-2013

Hassan¹,

Madboly²

2013

IOSR-JESTFT

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Correlation between Serum Creatine Phosphokinase and Severity of Acute Organophosphorus Poisoning: A Prospective Clinical Study (2012-2013

Hassan¹,

Madboly²

2013

IOSR-JESTFT

View full text Add to dashboard Cite

show abstract

“…In the fall of 1994, officials in Ohio discovered that methyl parathion (MP) had been used for domestic pest control, primarily in inner-city homes (1)(2)(3). Further investigations uncovered that an unlicensed operator had illegally applied MP in hundreds of homes for cockroach control.…”

mentioning

confidence: 99%

Measurement of p-nitrophenol in the urine of residents whose homes were contaminated with methyl parathion.

Barr

Turner

DiPietro

et al. 2002

Environ Health Perspect

Self Cite

View full text Add to dashboard Cite

We thank all the state and local health officials involved with sample collections and shipments. Throughout the period of laboratory-based measurements, many people provided invaluable assistance in biomonitoring that contributed to the rapid turnaround of data. We thank D. Methyl ParathionDuring the last several years, illegal commercial application of methyl parathion (MP) in domestic settings in several U.S. Southeastern and Midwestern States has affected largely innercity residents. As part of a multiagency response involving the U.S. Environmental Protection Agency (U.S. EPA), the Agency for Toxic Substances and Disease Registry (ATSDR), and state and local health departments, our laboratory developed a rapid, high-throughput, selective method for quantifying p-nitrophenol (PNP), a biomarker of MP exposure, using isotope dilution high-performance liquid chromatography-tandem mass spectrometry. We measured PNP in approximately 16,000 samples collected from residents of seven different states. Using this method, we were able to receive sample batches from each state; prepare, analyze, and quantify the samples for PNP; verify the results; and report the data to the health departments and ATSDR in about 48 hr. These data indicate that many residents had urinary PNP concentrations well in excess of those of the general U.S. population. In fact, their urinary PNP concentrations were more consistent with those seen in occupational settings or in poisoning cases. Although these data, when coupled with other MP metabolite data, suggest that many residents with the highest concentrations of urinary PNP had significant exposure to MP, they do not unequivocally rule out exposure to PNP resulting from environmental degradation of MP. Even with their limitations, these data were used with the assumption that all PNP was derived from MP exposure, which enabled the U.S. EPA and ATSDR to develop a comprehensive, biologically driven response that was protective of human health, especially susceptible populations, and included clinical evaluations, outreach activities, community education, integrated pest management, and decontamination of homes.

show abstract

“…Classical symptoms of methyl parathion poisoning are: headaches, nausea, night-waking (sleeplessness), diarrhea, restlessness, difficulty breathing, dizziness, abdominal cramps, excessive sweating, in-coordination excessive salivation and mental confusion [28].…”

Section: General Health Effectsmentioning

confidence: 99%

Review on Bioremediation of Methyl Parathion Contaminated Agricultural Soil by Microorganisms

2017

IJAPSA

View full text Add to dashboard Cite

Organophosphate pesticides are widely used for crop protection against pests and also to increase crop productivity. Methyl parathion (O, O-dimethyl O-p-nitrophenyl phosphorothioate, MP) is one such organophosphate pesticide. The extensive use of it has led to bioaccumulation in the environment. Thus causing harmful health hazards like inhibition of acetylcholinesterase (an important enzyme in nervous system) activity. Bioremediation, a technique can be applied to overcome bioaccumulation caused by pesticide. The present review is focused on the bioremediation of methyl parathion by degradation through potential soil bacteria and culturing them by immobilization. Also the new perspectives for the bioremediation would enhance in effective degradation of methyl parathion.

show abstract

Assessment of human exposure and human health effects after indoor application of methyl parathion in Lorain County, Ohio, 1995-1996.

Cited by 37 publications

References 17 publications

Correlation between Serum Creatine Phosphokinase and Severity of Acute Organophosphorus Poisoning: A Prospective Clinical Study (2012-2013

Correlation between Serum Creatine Phosphokinase and Severity of Acute Organophosphorus Poisoning: A Prospective Clinical Study (2012-2013

Measurement of p-nitrophenol in the urine of residents whose homes were contaminated with methyl parathion.

Review on Bioremediation of Methyl Parathion Contaminated Agricultural Soil by Microorganisms

Contact Info

Product

Resources

About