Assessment of Right Ventricular Function Using 2D Speckle Tracking Echocardiography in End Stage Renal Disease Patients on Regular Dialysis..

Abstract

Background: Chronic kidney disease (CKD) seems to be a serious issue which is becoming increasingly prevalent worldwide. The prevalence of hypertension, DM, and cardiovascular illnesses all contribute to an increase in the burden of CKD. Aim of the study: to assess the RV functions in chronic hemodialysis patients using speckle tracking echocardiography as a noninvasive method of assessment. Patients and Methods: This study included 50 patients on chronic hemodialysis (group I) were compared with 10 healthy individuals (group II) of matched age and gender. Results: Right ventricular global longitudinal strain (RVLS) was significantly reduced in hemodialysis patients. RVLS was shown to be significantly inversely related to age and RV diameters (longitudinal diameter and mid cavity diameter) and tricuspid E∕A ratio. While it showed significant positive correlation with FAC and LV ejection fraction. The E wave velocity of the tricuspid valve and the tricuspid E/A ratio were both substantially lower in group I patients. The A \ wave velocity of the tricuspid valve was considerably higher in group I patients. A significant decrease was observed in the E \ and S velocities of the tricuspid valve in group I patients, whereas the A velocities of the tricuspid valve were significantly enhanced. MPI was significantly increased in group I patients. Conclusion:Patients with chronic hemodialysis had greater RV and RA dimensions, lower RV FAC and TAPSE and reduced RVLS. RVLS was shown to be significantly inversely related to age and RV diameters, RA maximal volume and tricuspid E∕A ratio. While it showed significant positive correlation with FAC and LV ejection fraction.