Associação entre Escores de Risco Clínico (HEART, GRACE e TIMI) e Complexidade Angiográfica na Síndrome Coronária Aguda sem Elevação do Segmento ST

Cedro, A; Mota, Diandro Marinho; Ohe, Louis Nakayama; Timerman, Ari; Costa, J. Ribamar; Castro, Laura De

doi:10.36660/abc.20190417

Cited by 11 publications

(11 citation statements)

References 13 publications

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“…Interestingly, a cut-off value of >4 and ≥140 for HEART and GRACE scores yielded a sensitivity and specificity of 100% and 97%, respectively, to predict such severe CAD. 14 Given the abovementioned results, it is proposed that the combined use of the HEART and GRACE scores might be useful in detecting complex CAD. 14 It should be noted, however, that this is a small exploratory single-center study, mostly including patients with UA (in whom the GRACE score has not been extensively validated, as far as prognosis is concerned).…”

Section: Finally How Should I Treat This Patient With Nste-acs?mentioning

confidence: 99%

“…14 Given the abovementioned results, it is proposed that the combined use of the HEART and GRACE scores might be useful in detecting complex CAD. 14 It should be noted, however, that this is a small exploratory single-center study, mostly including patients with UA (in whom the GRACE score has not been extensively validated, as far as prognosis is concerned). Nonetheless, it would be an alluring hypothesis to investigate whether these scores might be incorporated as a valid tool in the pathway of care of NSTE-ACS patients, namely: (1) Could these be used as a novel criterion for immediate invasive strategy listing?, and (2) Could these differentiate between patients in whom P2Y12 pre-treatment strategy is safe and desirable from those in whom it might cause harm (e.g.…”

Section: Finally How Should I Treat This Patient With Nste-acs?mentioning

confidence: 99%

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SCA-SSST na Emergência: Você Consegue Adivinhar o que está sob o Guarda-Chuva?

Rocha¹,

Aguiar²

2021

Arquivos Brasileiros De Cardiologia

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Section: Finally How Should I Treat This Patient With Nste-acs?mentioning

confidence: 99%

Section: Finally How Should I Treat This Patient With Nste-acs?mentioning

confidence: 99%

SCA-SSST na Emergência: Você Consegue Adivinhar o que está sob o Guarda-Chuva?

Rocha¹,

Aguiar²

2021

Arquivos Brasileiros De Cardiologia

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“…Though multiple studies have shown positive associations between the HEART and TIMI scores and the angiographic extent of CAD and have been shown to be predictive of clinically significant CAD, none of these studies have specifically addressed patients with ESRD [13][14][15][16][17][18][19][20][21]. This study aims to determine whether the HEART and TIMI scores are adequate predictors of severe CAD in patients with ESRD.…”

Section: Introductionmentioning

confidence: 99%

HEART and Thrombolysis in Myocardial Infarction (TIMI) Scores Predict Severe Coronary Atherosclerosis in Patients With End-Stage Renal Disease

Parikh¹,

Aziz²,

Mackoff³

et al. 2023

Cureus

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History, EKG, age, risk factors, and troponin (HEART) and thrombolysis in myocardial infarction (TIMI) risk calculators have been validated to predict the risk of subsequent acute coronary syndromes and in some studies, severe coronary atherosclerosis in patients with a concerning clinical history. Their performance in patients with end-stage renal disease (ESRD), a population with a high pretest probability for the condition, is unknown. We aimed to determine whether HEART and TIMI scores can predict severe coronary atherosclerosis in patients with end-stage renal disease (ESRD). MethodsA single-center retrospective cohort of admitted patients aged 18 years or older with ESRD on dialysis who underwent coronary angiography during admission (November 2010 to December 2017) was retrospectively reviewed. The outcome of coronary angiography was compared with the calculated HEART and TIMI scores at the time of presentation. Receiver operating characteristics and logistic regression models were used to determine optimal score cutoffs, score usefulness, and associations between outcomes, scores, and patient characteristics. ResultsAmong 231 patient encounters, the mean HEART and TIMI scores were 6±2 and 3±1 points, respectively. Patients with diabetes mellitus, those 65 years old and older, and those reported to have angina pectoris were more likely to show severe coronary artery disease (CAD) lesions. Optimal score cutoffs for determining severe coronary lesions were between six and seven (area under the curve (AUC)=0.754, confidence interval (CI): 0.682-0.826) and between three and four (AUC=0.716, CI: 0.640-0.792) for the HEART and TIMI scores, respectively. ConclusionSimilar to the general population, HEART and TIMI scores can predict severe coronary atherosclerosis in the complex ESRD population.

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“…Globally, ACS is common cause of adult deaths accounting for 30% mortality rate. Risk stratification is a key component for initial assessment of ACS that differentiates low and high risk patients to avoid life threatening consequences via early medical management of high risk cases 7 . American cardiac association and European heart academy widely recommend the use of thrombolysis in myocardial infarction (TIMI) score for timely prognosis in ACS both STEMI & NSTEMI 8 .…”

Section: Introductionmentioning

confidence: 99%

Correlation of TIMI score with severity of coronary artery disease in acute coronary syndrome

Hasan

Iqbal

Tawab³

et al. 2022

Pak. j. Cardio vas. int. (print/Online)

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Background: ACS presents as wide range of clinical ailments that requires prompt treatment to avoid unforeseen circumstances. As noninvasive strategy, TIMI risk assessment is a widely accepted tool for risk stratification of ACS patient to initiate timely management. Purpose of the present study is to determine the association of TIMI score in predicting the severity of coronary artery disease in ACS. Methodology: A cross-sectional study was conducted in specialized tertiary care cardiac hospital on 255 patients from January 2021 to June 2021. For all patients, TIMI score calculated based on all the seven variables. Confidentiality of the participants was maintained. Ethical approval was obtained from review board of concerned hospital. Data was analyzed on SPSS version 23.0. One way ANOVA was used to compare categorical variables. Chi square test used to reveal difference in proportion to three TIMI groups. Results: Finding show that ST segment deviation was evident in 51.5% patients. Out of 37 patients in group-III with ST segment changes, 91.8% were found of having significant CAD. Results show that in group-III, 54.1% had significant three vessel CAD compared to 17.6% group-II & 7.5% group-I patients. Also, p-value of <0.001 depict significant association between TIMI score and severity of CAD. Conclusion: A significant association from this study gives a notion that TIMI score is valuable tool in clinical setting to make urgent decision regarding the management of CAD. Also, it was concluded from current study that patients with higher TIMI score had additional risk of three vessel CAD and left main vessel CAD in patients with ACS.

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Associação entre Escores de Risco Clínico (HEART, GRACE e TIMI) e Complexidade Angiográfica na Síndrome Coronária Aguda sem Elevação do Segmento ST

Cited by 11 publications

References 13 publications

SCA-SSST na Emergência: Você Consegue Adivinhar o que está sob o Guarda-Chuva?

SCA-SSST na Emergência: Você Consegue Adivinhar o que está sob o Guarda-Chuva?

HEART and Thrombolysis in Myocardial Infarction (TIMI) Scores Predict Severe Coronary Atherosclerosis in Patients With End-Stage Renal Disease

Correlation of TIMI score with severity of coronary artery disease in acute coronary syndrome

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