Association between adherence to the Mediterranean diet with cardiometabolic risk factors: a cross-sectional study on PERSIAN cohort study in Fasa

Bagheri, Milad; Nouri, Mehran; Homayounfar, Reza; Akhlaghi, Masoumeh

doi:10.1038/s41598-023-41935-3

Cited by 2 publications

(1 citation statement)

References 32 publications

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“…The validity and reliability of this questionnaire in stroke patients in Iran has already been investigated and confirmed [ 39 , 40 ]. Several previous studies have been used this FFQ for evaluation of dietary indices [ 41 , 42 ]. We opted for the completion of the Food Frequency Questionnaire (FFQ) by the patients’ family members due to several factors.…”

Section: Methodsmentioning

confidence: 99%

Association between dietary total antioxidant capacity and the risk of stroke: a nested case-control study

Habibzadeh,

Rahimlou,

Ravankhah

et al. 2024

BMC Nutr

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Background Oxidative stress after ischemic stroke contribute to neuronal cell injury. Unhealthy and unbalanced dietary patterns can increase the risk of several diseases, including stroke and cardiometabolic ones. However, the association between dietary total antioxidant capacity (DTAC) of antioxidant and stroke is controversial. Our study aimed to establish a correlation between DTAC and its impact on the occurrence of stroke. Methods This nested case–control study included 79 stroke cases and 158 healthy controls. We used data from the Fasa Adults Cohort Study (FACS) comprising 10,035 individuals at baseline. To assess the nutritional status of each individual, a 125-item food frequency questionnaire (FFQ) has been used to evaluate their dietary habits and intakes over the past year. DTAC was calculated using the ferric-reducing antioxidant power (FRAP) international databases. The stroke was confirmed by an experienced neurologist using standard imaging methods. Conditional logistic regression analyses were performed to evaluate the association between DTAC and stroke. Results The assessment of DTAC revealed that there was no statistically significant distinction between cases (mean ± SD: 5.31 ± 2.65) and controls (5.16 ± 2.80) with a p-value of 0.95. Even after adjusting for the potentially important confounding factors such as age, sex, event time, energy intake, smoking, hypertension, and diabetes, the association remains non-significant (adjusted odds ratio (OR) = 1.06, 95% CI: 0.94, 1.20, p-value = 0.33). Conclusions Our results did not confirm a significant link between DTAC and stroke risk. These findings emphasize the intricate interplay of factors influencing stroke risk and highlight the need for further research to unravel these relationships more comprehensively.

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Section: Methodsmentioning

confidence: 99%

Association between dietary total antioxidant capacity and the risk of stroke: a nested case-control study

Habibzadeh,

Rahimlou,

Ravankhah

et al. 2024

BMC Nutr

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Dietary antioxidant index and hypertension in the Iranian population: a nested case–control study within the Fasa adults cohort study

Firooznia,

Rahimlou,

Sekhavati

et al. 2024

Front. Nutr.

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IntroductionHypertension (HTN) is a prevalent condition associated with numerous cardiovascular and non-cardiac complications. Lifestyle interventions, including dietary adjustments, offer promising avenues for hypertension management. However, the precise relationship between dietary antioxidants and hypertension risk necessitates further investigation. This study aimed to elucidate the association between the Dietary Antioxidant Index (DAI) and hypertension risk using a nested case–control design.MethodA matched nested case–control study was conducted within the Fasa Adult Cohort Study (FACS), comprising 975 participants aged 35–70 years. Cases (n = 325) were hypertensive patients, while controls (n = 650) were individuals without hypertension, matched for sex and age. Dietary intake was assessed using a validated food frequency questionnaire, and DAI was computed based on standardized intake of antioxidants. Conditional logistic regression models were employed to evaluate the association between DAI and hypertension risk, adjusting for confounding variables.ResultsA significant inverse correlation was observed between DAI and hypertension risk across all models (OR = 0.89; 95% CI = 0.86–0.93, p < 0.001). This association remained robust after adjusting for potential confounders, including BMI, smoking, lipid profile, blood glucose levels, and educational status. In conclusion, higher DAI values were associated with a reduced risk of hypertension, highlighting the potential benefits of antioxidant-rich diets in hypertension prevention.ConclusionThese findings underscore the importance of dietary interventions as a complementary approach to hypertension management.

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Association between adherence to the Mediterranean diet with cardiometabolic risk factors: a cross-sectional study on PERSIAN cohort study in Fasa

Cited by 2 publications

References 32 publications

Association between dietary total antioxidant capacity and the risk of stroke: a nested case-control study

Association between dietary total antioxidant capacity and the risk of stroke: a nested case-control study

Dietary antioxidant index and hypertension in the Iranian population: a nested case–control study within the Fasa adults cohort study

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