Association between Age and Twenty Chemical Element Contents in Intact Thyroid of Males

Vladimir, Zaichick; Sofia, Zaichick

doi:10.36876/smggr.1014

Cited by 11 publications

(9 citation statements)

References 6 publications

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“…As was shown before 33,34 2 and Table 3. The mean values and all selected statistical parameters were calculated for twenty ChE (Al, B, Ba, Br, Ca, Cl, Cu, Fe, I, K, Li, Mg, Mn, Na, P, S, Si, Sr, V, and Zn) mass fractions (Table 1).…”

Section: Precision and Accuracy Of Resultssupporting

confidence: 68%

“…Level of I in the normal thyroid was investigated in relation to age, gender and some nonthyroidal diseases [23][24] . After that, variations of ChE content with age in the thyroid of males and females were studied and age-and gender-dependence of some ChE was observed [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] . Furthermore, a significant difference between some ChE contents in normal and cancerous thyroid was demonstrated [42][43][44][45][46][47] .…”

Section: Introductionmentioning

confidence: 99%

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Comparison of Levels of Twenty Chemical Elements in Normal Thyroid Tissue and Hypertrophic Thyroid Tissue

Zaichick

2021

Univ J Pharm Res

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Background: Goiter can appear as a palpable or visible enlargement of the thyroid gland at the base of the neck. If the goiter is accompanied by hypothyroidism or hyperthyroidism, it may be accompanied by symptoms of the underlying disorder, and nodular goiter (NG) is a health problem of international importance. The aim of this exploratory study was to assess whether there were significant changes in thyroid tissue levels of twenty chemical elements (ChE) Al, B, Ba, Br, Ca, Cl, Cu, Fe, I, K, Li, Mg, Mn , Na, P, S, Si, Sr, V, and Zn are present in the goitrous transformed thyroid. Methods: Thyroid tissue level of twenty ChE was prospectively evaluated in 46 patients with NG and 105 healthy populations. The measurements were performed using a combination of non-destructive and destructive methods: instrumental neutron activation analysis and inductively coupled plasma atomic emission spectrometry, respectively. Tissue samples were divided into two parts. One was used for morphological study while the other was for ChE analysis. Results: It was found that contents of Al, B, Br, Cl, Cu, Fe, Li, Mg, Mn, Na, P, S, Si, V, and Zn are significantly higher while the I levels are lower in NG than in normal tissues. Conclusion: There are considerable changes in ChE contents in goitrous tissue of thyroid. Thus, it is reasonable to assume that the levels of these ChE in thyroid tissue can be used as NG markers. However, this topic needs additional studies. Peer Review History: Received: 19 July 2021; Revised: 11 August; Accepted: 4 September, Available online: 15 September 2021 Academic Editor: Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, ahmad.najib@umi.ac.id UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file: Reviewer's Comments: Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 8.0/10 Reviewers: Prof. Dr. Hassan A.H. Al-Shamahy, Sana'a University, Yemen, shmahe@yemen.net.ye Prof. Cyprian Ogbonna ONYEJI, Obafemi Awolowo University, Ile-Ife, Nigeria, conyeji@oauife.edu.ng Similar Articles: VITAMIN A, RETINOIC ACID AND TAMIBAROTENE, A FRONT TOWARD ITS ADVANCES: A REVIEW

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Section: Precision and Accuracy Of Resultssupporting

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Comparison of Levels of Twenty Chemical Elements in Normal Thyroid Tissue and Hypertrophic Thyroid Tissue

Zaichick

2021

Univ J Pharm Res

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“…The ratios of means and the comparison of mean values of Ag, Co, Cr, Fe, Hg, I, Rb, Sb, Sc, Se, and Zn mass fractions in pair of sample groups such as NT and TBN, NT and TMN, and also TBN and TMN is presented in Table 2. The comparison of our results with published data (from 1990 year) for I mass fraction in NT [27,28,[31][32][33][34]37,[53][54][55][56][57][58][59][60][61][62][63][64][65][66][67][68][69][70][71][72], TBN [54,56,57,62,63,[67][68][69][70][71][72][73][74][75][76][77][78][79][80], and TMN [54,56,…”

Section: Resultsmentioning

confidence: 61%

“…Iodine level in the normal thyroid was investigated in relation to age, gender and some non-thyroidal diseases [23,24]. After that, variations of many TEs content with age in the thyroid of males and females were studied and age-and genderdependence of some TEs was observed [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41]. Furthermore, a significant difference between some TEs contents in colloid goiter, thyroiditis, thyroid adenoma, and cancer in comparison with normal thyroid and thyroid tissue adjacent to TNs was demonstrated [42][43][44][45][46][47][48].…”

Section: Introductionmentioning

confidence: 99%

Diagnosis of thyroid malignancy using trace elements of nodular tissue determined by neutron activation analysis

Zaichick¹

2022

World J. Adv. Res. Rev.

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Thyroid benign (TBN) and malignant (TMN) nodules are a common thyroid lesion. The differentiation of TMN often remains a clinical challenge and further improvements of TMN diagnostic accuracy are warranted. The aim of present study was to evaluate possibilities of using differences in trace elements (TEs) contents in nodular tissue for diagnosis of thyroid malignancy. Contents of TEs such as silver (Ag), cobalt (Co), chromium (Cr), iron (Fe), mercury (Hg), iodine (I), rubidium (Rb), antimony (Sb), scandium (Sc), selenium (Se), and zinc (Zn) were prospectively evaluated in “normal” thyroid (NT) of 105 individuals as well as in nodular tissue of thyroids with TBN (79 patients) and to TMN (41 patients). Measurements were performed using non-destructive instrumental neutron activation analysis. It was observed that in TMN tissue the mean mass fraction of I was lower while the mean mass fraction of Rb was higher than in NT and TBN tissue. It was demonstrated that I content in nodular tissue is the most informative parameter for the diagnosis of thyroid malignancy. It was found that “Sensitivity”, “Specificity” and “Accuracy” of TMN identification using the I level in the needle biopsy of affected thyroid tissue was significantly higher than that using US examination and cytological test of fine needle aspiration biopsy. It was concluded that determination of the I level in a needle biopsy of TNs using non-destructive instrumental analytical method is a fast, reliable, and very informative diagnostic tool that can be successfully used as an additional test of thyroid malignancy identification.

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“…Iodine level in the normal thyroid was investigated in relation to age, gender and some non-thyroidal diseases [23,24]. After that, variations of many TEs content with age in the thyroid of males and females were studied and age-and gender-dependence of some TEs was observed [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41]. Furthermore, a significant difference between some TEs contents in colloid goiter, thyroiditis, and thyroid adenoma in comparison with normal thyroid was demonstrated [42][43][44][45][46].…”

Section: Introductionmentioning

confidence: 99%

Content of Eleven Trace Elements in Thyroid Malignant Nodules and Thyroid Tissue adjacent to Nodules

Zaichick

2021

IGWHC

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Association between Age and Twenty Chemical Element Contents in Intact Thyroid of Males

Cited by 11 publications

References 6 publications

Comparison of Levels of Twenty Chemical Elements in Normal Thyroid Tissue and Hypertrophic Thyroid Tissue

Comparison of Levels of Twenty Chemical Elements in Normal Thyroid Tissue and Hypertrophic Thyroid Tissue

Diagnosis of thyroid malignancy using trace elements of nodular tissue determined by neutron activation analysis

Content of Eleven Trace Elements in Thyroid Malignant Nodules and Thyroid Tissue adjacent to Nodules

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