Association between bedtime and the prevalence of newly diagnosed non‐alcoholic fatty liver disease in adults

Wang, Honglei; Gu, Yeqing; Zheng, Lixiao; Liu, Li; Meng, Guang; Wang, Hongmei; Xia, Yang; Bao, Xue; Shi, Hongbin; Sun, Shaomei; Wang, Xing; Zhou, Ming; Jia, Qiyu; Song, Kun; Zhang, Qing; Niu, Kaijun

doi:10.1111/liv.13896

Cited by 38 publications

(19 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They all had received health examinations and completed lifestyle questionnaires. The study aimed to investigate the associations between chronic low‐grade systemic inflammation and health status of the general population . Participants were recruited from health management centres and community management centres.…”

Section: Methodsmentioning

confidence: 99%

Association between nut consumption and non‐alcoholic fatty liver disease in adults

Zhang

et al. 2019

Liver International

Self Cite

View full text Add to dashboard Cite

Background & Aims Increased nut consumption has been associated with reduced inflammation, insulin resistance, and oxidative stress. Although these factors are closely involved in the pathogenesis of non‐alcoholic fatty liver disease (NAFLD), few studies have focused on the association between nut consumption and NAFLD in the general population. We aimed to investigate the association of nut consumption and NAFLD in an adult population. Methods A total of 23 915 participants from Tianjin Chronic Low‐Grade Systemic Inflammation and Health (TCLSIH) Cohort Study were included in this study. Information on dietary intake was collected using a validated food frequency questionnaire. Abdominal ultrasonography was done to diagnose NAFLD. Multivariable logistic regression was used to assess the association of nut consumption with NAFLD. Results After adjusting for sociodemographic, medical, dietary, and lifestyle variables, the odds ratios (95% confidence interval) for NAFLD across categories of nut consumption were 1.00 (reference) for <1 time/week, 0.91 (0.82, 1.02) for 1 time/week, 0.88 (0.76, 1.02) for 2‐3 times/week, and 0.80 (0.69, 0.92) for ≥4 times/week (P for trend < 0.01). These associations were attenuated but remained significant after further adjustment for blood lipids, glucose, and inflammation markers. Conclusions Higher nut consumption was significantly associated with lower prevalence of NAFLD. Further prospective studies and randomized trials are required to ascertain the causal association between nut consumption and NAFLD.

show abstract

Section: Methodsmentioning

confidence: 99%

Association between nut consumption and non‐alcoholic fatty liver disease in adults

Zhang

et al. 2019

Liver International

Self Cite

View full text Add to dashboard Cite

show abstract

“…The Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) Cohort Study is an ongoing prospective cohort study. Detailed descriptions of the TCLSIH Cohort Study have been published previously (14,15) . Briefly, the study was initiated in 2007 and all participants underwent a real-time ultrasonographic examination as part of health examinations since January 2010.…”

Section: Study Design and Participantsmentioning

confidence: 99%

Association between edible mushroom intake and the prevalence of newly diagnosed non-alcoholic fatty liver disease: results from the Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study in China

Zhang

Lü

et al. 2019

Br J Nutr

Self Cite

View full text Add to dashboard Cite

Animal studies have suggested that mushroom intake can alleviate non-alcoholic fatty liver disease (NAFLD) due to its anti-inflammatory and antioxidant properties. However, the association between mushroom intake and NAFLD is unknown in humans. We aimed to investigate the association of mushroom intake with NAFLD among Chinese adults. This is a cross-sectional study of 24 236 adults (mean (standard deviation) age: 40·7 (sd 11·9) years; 11 394 men (47·0 %)). Mushroom intake was assessed via a validated FFQ. Newly diagnosed NAFLD was identified based on the results of annual health examinations, including ultrasound findings and a self-reported history of the disease. Multiple logistic models were used to examine the association between mushroom intake and NAFLD. The prevalence of newly diagnosed NAFLD was 19·0 %. Compared with those consuming mushrooms less frequently (≤1 time/week), the fully adjusted OR of newly diagnosed NAFLD were 0·95 (95 % CI 0·86, 1·05) for those consuming 2–3 times/week and 0·76 (95 % CI 0·63, 0·92) for those consuming ≥4 times/week (Pfor trend = 0·01). The inverse association was consistent in subgroups defined by age, sex and BMI. In conclusion, higher mushroom intake was significantly associated with lower prevalence of NAFLD among Chinese adults. Future research is required to understand the causal association between mushroom intake and NAFLD.

show abstract

“…And a validated food frequency questionnaire was also used to evaluate the total energy intake and dietary pattern score, including ‘‘fruits and sweets’’, ‘‘healthy’’ and ‘‘animal foods’’ dietary pattern score. Detailed information of dietary pattern score has been described elsewhere . Cancer and cardiovascular disease were based on self‐reported history.…”

Section: Methodsmentioning

confidence: 99%

“…Detailed information of dietary pattern score has been described elsewhere. 19 Cancer and cardiovascular disease were based on self-reported history. Participants with a history of cardiovascular disease or cancer but without limited mobility were also included in this study.…”

Section: Measurement Of Other Variablesmentioning

confidence: 99%

Vitamin D is related to handgrip strength in adult men aged 50 years and over: A population study from the TCLSIH cohort study

Wang

et al. 2019

Clinical Endocrinology

Self Cite

View full text Add to dashboard Cite

Summary Objective Handgrip strength (HGS) begins an accelerating decline around 50 years. Many of the studies performed in old adults have demonstrated a significant relationship between vitamin D and HGS, but the studies performed in participants with a broad age range have yielded conflicting results. The purpose of the study was to investigate the relationship between vitamin D and HGS using age 50 as a specific cut‐off. Design Population‐based, cross‐sectional study. Participants Totally 5102 participants (2911 males, 2191 females) from the TCLSIH Cohort. Measurements Serum concentration of 25‐hydroxyvitamin D (25(OH)D) was measured using an enzyme immunoassay. We divided participants into quartiles according to 25(OH)D, and the ranges for increasing quartiles were as follows: (males [≥50 years]: 10.94‐31.85, 31.88‐43.01, 43.20‐56.06, 56.20‐143.0; males [<50 years]: 11.11‐34.68, 34.71‐46.91, 46.96‐59.45, 59.50‐143.7; females [≥50 years]: 7.21‐30.01, 30.02‐40.18, 40.21‐52.44, 52.49‐275.4; females [<50 years]: 5.29‐28.91, 28.92‐40.19, 40.20‐51.90, 51.91‐140.2). HGS was measured with a hydraulic hand‐held dynamometer. Analysis of covariance was employed to explore the relationship. Results Among males aged above 50 years, the means (95% confidence interval) for HGS per body weight across the categories of serum 25(OH)D concentration were 0.523 (0.430‐0.638), 0.545 (0.447‐0.664), 0.543 (0.446‐0.661), 0.546 (0.449‐0.664) (Ptrend < 0.01) after adjustment for potential confounding factors. However, no relationships were observed between serum 25(OH)D concentration and HGS in males aged below 50 years and females in the whole age range. Conclusions Serum 25(OH)D concentration was significantly related to HGS in males aged above 50 years, independent of confounding factors. Future studies are needed to clarify the age and sex relationship between serum 25(OH)D concentration and HGS.

show abstract

Association between bedtime and the prevalence of newly diagnosed non‐alcoholic fatty liver disease in adults

Abstract: Late bedtime was slightly but significantly associated with an increased prevalence of newly diagnosed NAFLD, independently of confounding factors. It is suggested that early bedtime may be beneficial in preventing NAFLD.

Cited by 38 publications

References 52 publications

Association between nut consumption and non‐alcoholic fatty liver disease in adults

Association between nut consumption and non‐alcoholic fatty liver disease in adults

Association between edible mushroom intake and the prevalence of newly diagnosed non-alcoholic fatty liver disease: results from the Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study in China

Vitamin D is related to handgrip strength in adult men aged 50 years and over: A population study from the TCLSIH cohort study

Contact Info

Product

Resources

About