Association between Cognitive Decline and Oral Health Status in the Aging Population : A 5- year Observational study (Preprint)

Periodontal health, cognitive decline, and dementia: A systematic review and meta‐analysis of longitudinal studies

“…Forty seven studies were included in this review: 24 for cognitive decline 8,9,15–17,42–60 and 23 for dementia 10–14,47,61–77 (Figure 1). Characteristics of included studies are summarized in Table S1.…”

“…All 24 studies were population‐based longitudinal studies 8,9,15–17,42–60 . 23 studies included both male and female participants, 8,9,15–17,42,43,45–60 and 1 only male participants 44 .…”

“…All 24 studies were population‐based longitudinal studies 8,9,15–17,42–60 . 23 studies included both male and female participants, 8,9,15–17,42,43,45–60 and 1 only male participants 44 . 15 studies included participants aged ≥65 years at baseline, 8,15–17,43,45,46,49–52,54,55,58,60 while 9 studies also included younger participants 9,42,44,47,48,53,56,57,59 .…”

“…Much research has been focused on identifying modifiable risk factors, for example, cardiovascular diseases, smoking, and unhealthy diet, 5 and targeting them through various interventions (e.g., pharmacotherapy and/or lifestyle modification) 5–7 . Among the many risk factors for dementia and cognitive decline, oral health measures (e.g., periodontitis, tooth loss) have only started to be recently explored 8–17 …”

“…Periodontal health is an important health determinant linked to various systemic conditions (e.g., diabetes, cardiovascular diseases) 19 . The available evidence on periodontal health and cognitive deterioration is insufficient and subject to limitations 8–17,20–30 . Most individual studies lack comprehensive exposure and outcome assessments and have a shorter duration.…”