Association between dental caries indicators and serum glycated hemoglobin-levels among patients with type 2 diabetes mellitus

Abstract

Diabetes mellitus (DM) with poor glycemic control is often linked to oral manifestations. This study aimed to investigate the association between dental caries (DC) and glycated hemoglobin (HbA1c) among patients with type 2 DM (T2DM). A health center-based cross-sectional study was conducted comprising 91 eligible patients with T2DM (21 males and 70 females) with a mean age (± standard deviation) of 61.49 ± 9.71 years. A structured interview, screening for DM-related factors, and oral examination were performed. Serum HbA1c levels were used as an index for glycemic control. A comparison between patients with controlled T2DM, i.e., HbA1c ≤7.0% (n = 46), and uncontrolled T2DM, i.e., HbA1c >7.0% (n = 45), showed significant differences in mean values of decayed teeth (DT) (P = 0.045); missing teeth (P = 0.002); and decayed, missing, and filled teeth (DMFT) index (P < 0.001). Results of multiple linear regression analysis revealed that the number of DT was significantly correlated with serum HbA1c levels (95% confidence interval [CI] 0.173 to 0.972, P = 0.005). Furthermore, DMFT index values and serum HbA1c levels (95% CI 0.532 to 1.658, P < 0.001) showed a significant association. This study provides substantial evidence on the association between DC indicators and serum HbA1c levels.

Prevalence of dental caries in patients with type II diabetes mellitus

“…From their analysis, it found that levels of HbA1c were also determined in diabetic patients of type 2 and control groups, and a strong association was identi ied between levels of HbA1c and serum glucose in diabetic and control groups, respectively. In a research conducted by (Majbauddin et al, 2019) patients with uncontrolled glycemic rates reported higher numbers of decayed teeth, missing teeth and DMFT index values than those with regulated glycemic rates which is consistent with our study indings.…”

Oral health status and oral health-related quality of life among patients with type 2 diabetes mellitus in the United Arab Emirates: a matched case-control study

“…The association between dental caries and diabetes mellitus is controversial [10,31]. Diabetes is associated with impaired salivary gland function and increased blood and salivary glucose concentrations, which favor oral bacterial growth, thus leading to an increased risk of developing dental caries [31][32][33]. Despite this possible biological explanation, the duration of diabetes may also be a contributing factor.…”

Prevalence of Prediabetes and Type 2 Diabetes Mellitus in Football Players: A Novel Multi Football Clubs Cross Sectional Study

“…After detailed interview, the participants were allocated an identification number, and a para-medical staff measured the HbA1c, by using the "Clover A1c system (Inforpia, Kyunggi, Korea), an automated boronate affinity assay for the determination of the percentage of HbA1c % in the whole body's blood" [13]. American Diabetes Association (ADA) [14] based criteria on glycated hemoglobin (HbA1c) was used to diagnose the diabetes mellitus.…”