Association between early‐life trauma and obsessive compulsive symptoms in community youth

Barzilay, Ran; Patrick, Ariana; Calkins, Monica E.; Moore, Tyler M.; Gur, Ruben C.; Gur, Raquel E.

doi:10.1002/da.22907

Cited by 38 publications

(18 citation statements)

References 52 publications

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“…Although similar findings have been found in non-pregnant individuals (i.e., relative imbalance of HF and LF with social phobia 66 ; lower HF; and increased LF/HF ratio with PTSD 24 – 26 ), this is the first time pregnant women with anxiety disorders were shown to have distinct HRV patterns. Those with OCD and those with exposure to childhood traumatic events had similar alterations in ANS functioning, supported by literature showing childhood trauma exposure has been associated with greater obsessive–compulsive symptoms, particularly in females 67 . Obsessive–compulsive symptoms are more commonly seen in perinatal patients 68 , 69 .…”

Section: Discussionsupporting

confidence: 65%

Heart rate variability in late pregnancy: exploration of distinctive patterns in relation to maternal mental health

et al. 2021

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Exploration of photoplethysmography (PPG), a technique that can be translated to the clinic, has the potential to assess the autonomic nervous system (ANS) through heart rate variable (HRV) in pregnant individuals. This novel study explores the complexity of mental health of individuals in a clinical sample responding to a task in late pregnancy; finding those with several types of past or current anxiety disorders, greater trait anxiety, or greater exposure to childhood traumatic events had significantly different HRV findings from the others in the cohort. Lower high frequency (HF), a measure of parasympathetic activity, was found for women who met the criteria for the history of obsessive–compulsive disorder (OCD) (p = 0.004) compared with women who did not meet the criteria for OCD, and for women exposed to greater than five childhood traumatic events (p = 0.006) compared with those exposed to four or less childhood traumatic events. Conversely higher low frequency (LF), a measure thought to be impacted by sympathetic system effects, and the LF/HF ratio was found for those meeting criteria for a panic disorder (p = 0.006), meeting criteria for social phobia (p = 0.002), had elevated trait anxiety (p = 0.006), or exposure to greater than five childhood traumatic events (p = 0.004). This study indicates further research is needed to understand the role of PPG and in assessing ANS functioning in late pregnancy. Study of the impact of lower parasympathetic functioning and higher sympathetic functioning separately and in conjunction at baseline and in relation to tasks during late pregnancy has the potential to identify individuals that require more support and direct intervention.

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Section: Discussionsupporting

confidence: 65%

Heart rate variability in late pregnancy: exploration of distinctive patterns in relation to maternal mental health

et al. 2021

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“…Furthermore, it accounts for a dimensional perspective were e.g. the exposure to a traumatic event has already been associated with an increased risk to endorsed at least one obsessive-compulsive symptom (Barzilay et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

Childhood trauma and coping in patients with psychotic disorders and obsessive-compulsive symptoms and in un-affected siblings

Renkema

Haan

Schirmbeck

et al. 2020

Child Abuse & Neglect

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Background: Research on environmental and individual riskfactors in patients with a psychotic disorder and co-occurring obsessivecompulsive symptoms (OCS) is limited. Objective: This study aimed to examine the role of childhood trauma and coping on the occurrence of OCS in patients with a psychotic disorder and on a subclinical level in siblings. Participants and setting: 626 patients and 638 siblings from the Genetic Risk and Outcome of Psychosis (GROUP) study were included in the current study. Methods: Differences between patients and siblings with and without OCS were analyzed with between-group comparisons. Mediation analyses investigated the effect of coping on the association between trauma and OCS severity. Results: Patients and siblings with OCS reported more childhood traumatic events, particularly sexual (OR=1.62 / 3.26) and emotional (OR=1.47 / 2.04) abuse compared to those without OCS. Both patients (d=0.69) and siblings (d=0.49) with co-occurring OCS showed a higher tendency for dysfunctional passive coping strategies compared to the group without OCS. The tendency for passive coping mediated the association between sexual and emotional abuse and OCS severity in patients. Conclusions: Results imply that childhood trauma is associated with the presence of co-occurring OCS. Enhancing active coping strategies might have a beneficial effect in the prevention and treatment of co-occurring OCS in patients with psychotic disorders.Dear Editor, attached you will find the revised version of our article with the title ´Childhood trauma and coping in patients with psychotic disorders and obsessive-compulsive symptoms and in un-affected siblings´.We are really grateful for the opportunity to have our work considered for publication in Child Abuse & Neglect. We have responded to the requested revisions. Changes made in the text have been highlighted in yellow.

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“…For one, there appears to be a direct association between trauma and the development of OCD symptoms (Cromer et al, 2007;Dykshoorn, 2014;Lochner et al, 2002;Real et al, 2011), with up to 70% of individuals presenting with OCD symptoms after experiencing a traumatic event (Fontenelle et al, 2012;Gershuny et al, 2008). Indeed, studies have shown that different types of trauma, such as assault, are predictive of more severe of OCD symptoms (Barzilay et al, 2019), and that past trauma is associated with greater OCD symptoms, particularly compulsions (Miller & Brock, 2017). Additionally, OCD and PTSD share some similarities in terms of symptoms, including repeated intrusive images and thoughts that produce intense anxiety and avoidance.…”

Section: Emdr and Ocdmentioning

confidence: 99%

Examination of Initial Evidence for EMDR as a Treatment for Obsessive-Compulsive Disorder

Talbot

2021

J EMDR Prac Res

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Obsessive-compulsive disorder (OCD) is a debilitating psychological condition that impacts millions of people globally. The front-line psychological intervention for OCD is exposure/response prevention (ERP), however, many individuals do not respond to this treatment approach. Eye movement desensitization and reprocessing (EMDR) is a new therapeutic option which could be effective in treating OCD. This review examined the initial evidence for the effectiveness of EMDR in reducing OCD symptoms. Nine studies were included in the review, including six case studies and three group studies. Results indicate that EMDR is a promising candidate for treating OCD, with all studies showing EMDR therapy resulted in reduced symptoms from baseline. Results also indicated that EMDR may be as effective as ERP, and more effective than selective serotonin reuptake inhibitors (SSRIs) in treating OCD.

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Association between early‐life trauma and obsessive compulsive symptoms in community youth

Cited by 38 publications

References 52 publications

Heart rate variability in late pregnancy: exploration of distinctive patterns in relation to maternal mental health

Heart rate variability in late pregnancy: exploration of distinctive patterns in relation to maternal mental health

Childhood trauma and coping in patients with psychotic disorders and obsessive-compulsive symptoms and in un-affected siblings

Examination of Initial Evidence for EMDR as a Treatment for Obsessive-Compulsive Disorder

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