Association between gestational age at delivery and lymphocyte-monocyte ratio in the routine second trimester complete blood cell count

Cha, Hyun-Hwa; Kim, Jong Mi; Kim, Hyun Mi; Kim, Mi Ju; Chong, Gun Oh; Seong, Won Joon

doi:10.12701/yujm.2020.00234

Cited by 7 publications

(3 citation statements)

References 19 publications

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“…This means there is no statistically significant age difference between the preterm and term labor groups. Previous studies stated no difference in maternal age between the preterm labor groups on the indication, spontaneous, or term preterm labor [20]. The results of this study were also presented by Daglar et al [21] that there is no difference in the mean age of the mother between groups with term labor, the threat of preterm labor, and preterm labor.…”

Section: A Characteristics Of the Research Samplesupporting

confidence: 83%

High Apoptotic Index in Amniotic Membrane of Pregnant Women is A Risk Factor for Preterm Labor

Wiradnyana,

Jaya Kusuma,

Anantasika

et al. 2023

EJMED

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This study aims to prove a high apoptotic index in the amniotic membrane as a risk factor for preterm Labor. Case-control study, comparing preterm and term groups (n=54) who underwent labor in Obstetrics Emergency Room, Sanglah Central General Hospital Denpasar, Bali. Apoptotic index is a method of identifying and assessing the quantity of tissue undergoing apoptosis, which in this study was the amniotic membrane tissue, calculated and stained using the TUNEL method. Data collected was subjected to further statistical tests. Normality test with Shapiro Wilk test, followed by parametric independent T-test and Mann Whitney test was performed. Cut off apoptotic index was determined using the Receiver Operating Characteristic (ROC) curve. Bivariate analysis with Chi-square test and calculation of odds ratio was performed to assess the high apoptotic index to the risk of preterm Labor. Statistical significance was obtained with p value <0.05. Based on the cut-off value of ROC, the apoptotic index was classified into high (≥37.5%) and low (<37.5%) apoptotic index. A high apoptotic index is a risk factor for preterm Labor and increases the risk 6 times greater than the group with a low apoptotic index (p=0.003; OR 5.714; 95% CI 1.764–18.507). High apoptotic index in the amniotic membranes of pregnant women is a risk factor for preterm Labor.

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Section: A Characteristics Of the Research Samplesupporting

confidence: 83%

High Apoptotic Index in Amniotic Membrane of Pregnant Women is A Risk Factor for Preterm Labor

Wiradnyana,

Jaya Kusuma,

Anantasika

et al. 2023

EJMED

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“…Inflammatory parameters, such as platelet count to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) can be calculated using complete blood count (CBC) test results [12]. The platelet count and indices, including mean platelet volume (MPV), platelet distribution width (PDW) and platelet large cell ratio (P-LCR) from the CBC test provide important information on the occurrence of gestational diabetes [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Platelet Count and Platelet Indices in Pregnant Saudi Women with Gestational Diabetes Mellitus

Alshehri

2021

CRDOJ

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To evaluate the differences in platelet count and platelet indices in the second trimester of pregnancy between pregnant women with gestational diabetes mellitus (GDM) and apparently healthy pregnant women. Methods:A cross-sectional study was performed with 60 pregnant women with GDM (cases) and 60 apparently healthy pregnant women (controls). The study groups were matched in terms of baseline characteristics; complete blood counts were done to determine platelet counts and platelet indices. Results:The mean total platelet count, MPV, PDW and P-LCR were significantly increased in pregnant women with GDM compared to the apparent healthy pregnant women (P value = 0.00). MPV was well correlated with PDW and P-LCR, and PDW was directly correlated with P-LCR. Conclusion:The high platelet count and the significant changes in platelet indices on CBC testing in the second trimester of pregnancy were most probably due to the presence GDM.

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“…Although there was no significant difference in CBC parameters, Cha et al [34] found that a higher LMR in the second trimester was associated with a lower gestational age at birth. In the present study, in line with the literature, a negative Pearson correlation was found between PLR and NLR and gestational age at birth.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Complete Blood Cell Count Parameters in the Diagnosis of Threatened Preterm Labor and Premature Rupture of Membranes

2022

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Purpose: The purpose of this study was to investigate a possible relationship between systemic inflammatory markers such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), lymphocyte monocyte ratio (LMR), threatened preterm labor (TPL), and preterm premature rupture of membranes (PPROM), using complete blood cell count (CBC) parameters. Method: The study was carried out prospectively with patients admitted to our university hospital due to preterm labor and at risk of PPROM. The cases were divided into three groups according to their pregnancy status. Group 1 consisted of 90 patients with PPROM between 24th and 36th gestational weeks; group 2, 115 patients diagnosed with TPL between 24th and 36th gestational weeks; group 3, 101 patients over 36 weeks of gestation (control) who were not in labor. In addition to the demographic data of the patients, CBC parameters (white blood cell (WBC), Hg, Hct, Plt, lymphocyte, monocyte, mean platelet volume, PLR, LMR, and NLR) and C-reactive protein (CRP) values were examined and compared in each of the three groups. Results: CRP and WBC values of group 1 (PPROM) were higher than group 2 (TPL) and group 3 (control) (p < 0.05 for both). Pearson correlation between the gestational age and PLR and NLR values was significant (r and p values for PLR and NLR, respectively, r = −0.18, p < 0.001; r = −0.23, p < 0.001). However, there was no significant difference between the groups regarding PLR, NLR, LMR, platelet, monocytes, and lymphocyte counts. Conclusions: Only WBC was a valuable parameter in predicting preterm labor and PPROM. Although there was no significant difference between the groups in PLR and NLR, a negative correlation was found with gestational age at delivery. CRP value is still a helpful parameter in PPROM and TPL prediction.

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Association between gestational age at delivery and lymphocyte-monocyte ratio in the routine second trimester complete blood cell count

Cited by 7 publications

References 19 publications

High Apoptotic Index in Amniotic Membrane of Pregnant Women is A Risk Factor for Preterm Labor

High Apoptotic Index in Amniotic Membrane of Pregnant Women is A Risk Factor for Preterm Labor

Platelet Count and Platelet Indices in Pregnant Saudi Women with Gestational Diabetes Mellitus

Evaluation of Complete Blood Cell Count Parameters in the Diagnosis of Threatened Preterm Labor and Premature Rupture of Membranes

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