Association between gut microbiota and bone metabolism: Insights from bibliometric analysis

Abstract

Gut microbiota has been reported to participate in bone metabolism. However, no article has quantitatively and qualitatively analyzed this crossing field. The present study aims to analyze the current international research trends and demonstrate possible hotspots in the recent decade through bibliometrics. We screened out 938 articles meeting the standards from 2001 to 2021 in the Web of Science Core Collection database. Bibliometric analyses were performed and visualized using Excel, Citespace, and VOSviewer. Generally, the annual number of published literatures in this field shows an escalating trend. The United States has the largest number of publications, accounting for 30.4% of the total. Michigan State University and Sichuan University have the largest number of publications, while Michigan State University has the highest average number of citations at 60.00. Nutrients published 49 articles, ranking first, while the Journal of Bone and Mineral Research had the highest average number of citations at 13.36. Narayanan Parameswaran from Michigan State University, Roberto Pacifici from Emory University, and Christopher Hernandez from Cornell University were the three professors who made the largest contribution to this field. Frequency analysis showed that inflammation (148), obesity (86), and probiotics (81) are keywords with the highest focus. Moreover, keywords cluster analysis and keywords burst analysis showed that “inflammation”, “obesity”, and “probiotics” were the most researched topics in the field of gut microbiota and bone metabolism. Scientific publications related to gut microbiota and bone metabolism have continuously risen from 2001 to 2021. The underlying mechanism has been widely studied in the past few years, and factors affecting the alterations of the gut microbiota, as well as probiotic treatment, are emerging as new research trends.

Bibliometric and visualization analysis of risk management in the doctor–patient relationship: A systematic quantitative literature review

“…A journal with a high number of publications means that it provides a broad platform for researchers to share their findings. [38] Table 2 describes the top 10 journals that published the highest number of papers on risk management in the DPR and their specific information. It could be seen that Patient Education and Counseling has the highest number of papers (17), followed by the Journal of General Internal Medicine (14), and BMJ Open (13).…”

“…These highly cited papers provide insight into the research directions and hot spots in the field. [38] Our analysis of highly cited papers showed that they focused on 4 aspects of risk management in the DPR: how to improve the DPR to enhance patient adherence [43–46] ; exploring the contribution of doctor–patient interaction to aspects of disease counseling, [47] quality tests of doctor–patient interaction, [48] and measuring patients’ perceptions of the DPR. [49] Highly cited authors are important drivers of scholarly innovation and disciplinary development in a field, [50] and the largest number of publications is 4, which indicates that a stable and obvious core team has not yet been formed in this field.…”

Research trends on the gut microbiota in endocrine metabolism: a thematic and bibliometric analysis

“…The analysis herein is crafted to address the noted scarcity of comprehensive bibliometric analyses that encompass the entire spectrum of endocrinology and metabolism research. While there exist segmented bibliometric studies focusing on specific intersections within the field-such as the gut microbiota's role in diabetes, the impact on bone health, and the interplay with obesityour research intends to bridge the gap by delivering a holistic overview of the research landscape (Zhang et al, 2022;Zhang et al, 2023;Su et al, 2023).…”

Unveiling the hidden world of gut health: Exploring cutting-edge research through visualizing randomized controlled trials on the gut microbiota

“…The interpretation of research and scientific discoveries related to RCTs involving gut microbiota is not fully studied. However, ongoing research in this area will probably persist, as suggested by studies that are akin to those centered on microbiota[ 20 - 22 ], including investigations into the role of the gut microbiota in schizophrenia[ 23 ], nutrition[ 24 ], bone metabolism[ 25 ], cardiovascular diseases[ 26 - 28 ], atherosclerosis[ 29 ], diabetes (both type 1 and type 2)[ 30 , 31 ], irritable bowel syndrome[ 32 , 33 ], depression[ 34 ], autoimmune diseases[ 35 ], rheumatoid arthritis[ 36 ], attention deficit and hyperactivity disorder[ 37 ], cancer[ 38 - 42 ], the microbiome-gut-brain axis[ 38 - 42 ], and fecal microbiota transplantation[ 43 - 47 ].…”