Association Between Heavy Metals Exposure and Height in Chinese Preschoolers

Abstract

Objectives This study aimed to explore the association between multiple metals' exposure and children's height. Methods We collected urine samples and physical measurement data of 1477 preschoolers in China. Children's actual height was measured, and whether reached target height was also assessed. Logistic regression analysis was performed to explore the association between heavy metals and height. The least absolute shrinkage and selection operator regression was used to select the urinary metals, which were highly correlated. Results In the single-metal model after adjusting for potential confounders, urinary iron, aluminum, nickel, chrome, titanium, vanadium, selenium, rubidium, and thallium levels were negatively associated with actual height. Urinary iron, aluminum, nickel, and chrome concentrations were also negatively associated with target height. Conclusions The findings suggested that some urinary metal exposure might be associated with height in preschoolers.