Association between Hepatitis B virus and gastric cancer: A systematic review and meta-analysis

Yu, Rong; Huang, Jingru; Peng, Hewei; Yin, Shuo; Xie, Weijiang; Ren, Shutong; Peng, Xian-E

doi:10.1016/j.imj.2023.04.003

Cited by 2 publications

(1 citation statement)

References 28 publications

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“…HBV has been widely known to play a vital role in developing hepatocellular carcinoma [113,114]. Some recent meta-analyses have shown that HBV infection could also significantly increase people's risk of developing GC [115,116], but the data on such an association were still limited and not robust. A Kailuan cohort study found a nonsignificant association between HBV infection and GC [117].…”

Section: Infection Of Hbv and Hcvmentioning

confidence: 99%

Exploring the Microbiome in Gastric Cancer: Assessing Potential Implications and Contextualizing Microorganisms beyond H. pylori and Epstein-Barr Virus

Shin,

Xie,

Chen

et al. 2023

Cancers

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While previous research has primarily focused on the impact of H. pylori and Epstein-Barr virus (EBV), emerging evidence suggests that other microbial influences, including viral and fungal infections, may also contribute to gastric cancer (GC) development. The intricate interactions between these microbes and the host’s immune response provide a more comprehensive understanding of gastric cancer pathogenesis, diagnosis, and treatment. The review highlights the roles of established players such as H. pylori and EBV and the potential impacts of gut bacteria, mainly Lactobacillus, Streptococcus, hepatitis B virus, hepatitis C virus, and fungi such as Candida albicans. Advanced sequencing technologies offer unprecedented insights into the complexities of the gastric microbiome, from microbial diversity to potential diagnostic applications. Furthermore, the review highlights the potential for advanced GC diagnosis and therapies through a better understanding of the gut microbiome.

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